申请人:INNOBIO CORPORATION LIMITED
公开号:US10555909B2
公开(公告)日:2020-02-11
Microencapsulation of β-alanine uses β-alanine as a core material and a mixture of a wall material and an additive as a release material. The additive comprises: a fatty acid-based saturated or unsaturated fatty acid glyceride containing 12-22 carbon atoms and a phospholipid. The fatty acid glyceride is a mono-fatty acid glyceride or a di-fatty acid glyceride, or a mixture formed by mixing the mono-fatty acid glyceride and the di-fatty acid glyceride at arbitrary proportions. The microencapsulation technique solves problems occurring with the use of β-alanine as a raw material, such as high moisture absorption tendency thereof, unpleasant smell and stinging accompanying administration of the same. The invention selects and combines the wall material and the additive to attain a balance between embedment and release with respect to a microencapsulated β-alanine product, and effectively optimizes release kinetics of the product, thereby enabling a stable release of the product, and realizing effective embedment and uniform release. Therefore, the microencapsulated β-alanine is applicable to the preparation of food, drugs, health-enhancing products and functional food.
β-丙氨酸的微胶囊以β-丙氨酸为核心材料,以壁材和添加剂的混合物为释放材料。添加剂包括:含有 12-22 个碳原子的脂肪酸基饱和或不饱和脂肪酸甘油酯和磷脂。脂肪酸甘油酯是单脂肪酸甘油酯或二脂肪酸甘油酯,或者是单脂肪酸甘油酯和二脂肪酸甘油酯以任意比例混合形成的混合物。微胶囊技术解决了以β-丙氨酸为原料时出现的问题,如吸湿性强、气味难闻、服用时刺痛等。本发明通过壁材和添加剂的选择和组合,使微胶囊β-丙氨酸产品在包埋和释放之间达到平衡,并有效优化产品的释放动力学,从而使产品稳定释放,实现有效包埋和均匀释放。因此,微胶囊β-丙氨酸适用于制备食品、药品、保健品和功能性食品。