3-氨基-4-(苯磺酰)噻吩-2-甲酸 | 175201-59-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3-氨基-4-(苯磺酰)噻吩-2-甲酸
• 英文名称: 3-Amino-4-(phenylsulfonyl)thiophene-2-carboxylic acid
• 英文别名: 3-amino-4-(benzenesulfonyl)thiophene-2-carboxylic acid
• CAS: 175201-59-9
• 化学式: C₁₁H₉NO₄S₂
• mdl: MFCD00067913
• 分子量: 283.3
• InChiKey: YXMYJEUQTGKJPV-UHFFFAOYSA-N

物化性质

• 熔点：
  174 °C

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  134
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 安全说明：
  S22,S24/25
• 海关编码：
  2934999090

文献信息

• Cyclic N-Hydroxy Imides as Inhibitors of Flap Endonuclease and Uses Thereof
  申请人：Tumey Lawrence N.

  公开号：US20080287465A1

  公开（公告）日：2008-11-20

  Acrylic n-hydroxy imides and their use in pharmaceutical compositions and in the inhibition of flap endonuclease are disclosed.

  本发明揭示了丙烯酸n-羟基亚酰亚胺及其在制药组合物和抑制皱褶内切酶方面的应用。
• PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS
  申请人：Rasmussen Jakob Ewald

  公开号：US20120116027A1

  公开（公告）日：2012-05-10

  The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of Growth Hormone from closely related proteins.
• US7947691B2
  申请人：——

  公开号：US7947691B2

  公开（公告）日：2011-05-24
• [EN] CYCLIC N-HYDROXY IMIDES AS INHIBITORS OF FLAP ENDONUCLEASE AND USES THEREOF<br/>[FR] N-HYDROXY-IMIDES SERVANT D'INHIBITEURS DE LA FLAP-ENDONUCLEASE ET LEURS UTILISATIONS
  申请人：ATHERSYS INC

  公开号：WO2006014647A2

  公开（公告）日：2006-02-09

  Acylic n-hydroxy imides and their use in pharmaceutical compositions and in the inhibition of flap endonuclease are disclosed.
• [EN] PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS<br/>[FR] PROCÉDÉ POUR L'ÉPURATION DE POLYPEPTIDES DE L'HORMONE DE CROISSANCE HUMAINE METTANT EN OEUVRE DES RÉSINES D'AFFINITÉ COMPORTANT DES LIGANDS SPÉCIFIQUES
  申请人：NOVO NORDISK AS

  公开号：WO2010055135A1

  公开（公告）日：2010-05-20

  The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of Growth Hormone from closely related proteins.