19-Sulfanylnonadecan-1-OL | 114896-31-0

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: 19-Sulfanylnonadecan-1-OL
• 英文别名: 19-sulfanylnonadecan-1-ol
• CAS: 114896-31-0
• 化学式: C₁₉H₄₀OS
• 分子量: 316.6
• InChiKey: CPKYVBYBSYKJLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  21
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Polymer parts
  申请人：Sony DADC Austria AG

  公开号：EP2792471A1

  公开（公告）日：2014-10-22

  A method of producing a polymer part comprising the following steps: (a) incorporating a hydrophobic small molecule into the polymer before, during or after manufacture of the polymer part, the hydrophobic small molecule and the polymer being essentially inert to one another; and (b) annealing the polymer part to induce migration of the hydrophobic small molecules to a surface of the polymer part to provide that surface with a specified degree of hydrophobicity defined by the combination of the polymer and the hydrophobic small molecule; is described. Polymer parts made according to the method are also described.

  一种生产聚合物部件的方法，包括以下步骤：(a) 在制造聚合物部件之前、期间或之后，将疏水性小分子掺入聚合物中，疏水性小分子和聚合物基本上互为惰性；以及 (b) 对聚合物部件进行退火处理，促使疏水性小分子迁移到聚合物部件的表面，使该表面具有由聚合物和疏水性小分子的组合确定的特定疏水性。还描述了根据该方法制造的聚合物部件。
• Method of producing a polymer part and polymer part
  申请人：STRATEC CONSUMABLES GmbH

  公开号：US10611890B2

  公开（公告）日：2020-04-07

  A method of producing a polymer part comprising the following steps: (a) incorporating a hydrophobic small molecule into the polymer before, during or after manufacture of the polymer part, the hydrophobic small molecule and the polymer being essentially inert to one another; and (b) annealing the polymer part to induce migration of the hydrophobic small molecules to a surface of the polymer part to provide that surface with a specified degree of hydrophobicity defined by the combination of the polymer and the hydrophobic small molecule; is described. Polymer parts made according to the method are also described.

  一种生产聚合物部件的方法，包括以下步骤：(a) 在制造聚合物部件之前、期间或之后，将疏水性小分子掺入聚合物中，疏水性小分子和聚合物基本上互为惰性；以及 (b) 对聚合物部件进行退火处理，促使疏水性小分子迁移到聚合物部件的表面，使该表面具有由聚合物和疏水性小分子的组合确定的特定疏水性。还描述了根据该方法制造的聚合物部件。
• Polymer slides having hydrophobic small molecules
  申请人：STRATEC Consumables GmbH

  公开号：US10800895B2

  公开（公告）日：2020-10-13

  A plurality of polymer slides, each having a polymer part with a first polymer surface portion uncoated and a second surface portion coated with a metal. The first and second surface portions each have different surface coating properties and have respective first and second specified degrees of hydrophobicity which are different from each other. A hydrophobic small molecule is located in the polymer part of each polymer slide, and the hydrophobic small molecule and the polymer are essentially inert to one another. Adjacent polymer slides are arranged in a manner that the first polymer surface of one slide faces a metal coated second surface portion of another slide. The hydrophobic small molecule evaporates from said first polymer surface portion of the polymer part of one polymer slide onto the adjacent metal coated second surface portion of another polymer slide.

  多个聚合物载玻片，每个载玻片都有一个聚合物部分，第一聚合物表面部分没有涂层，第二表面部分涂有金属。第一和第二表面部分各自具有不同的表面涂层特性，并具有各自不同的第一和第二疏水性。疏水小分子位于每个聚合物载玻片的聚合物部分，疏水小分子和聚合物之间基本上是惰性的。相邻聚合物载玻片的排列方式是，一个载玻片的第一聚合物表面朝向另一个载玻片的第二表面金属涂层部分。疏水小分子从一个聚合物载玻片的聚合物部分的第一聚合物表面蒸发到相邻的另一个聚合物载玻片的涂有金属的第二表面部分上。
• DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS
  申请人：Agrawal C. Mauli

  公开号：US20090123516A1

  公开（公告）日：2009-05-14

  Disclosed are medical devices comprising one or more surfaces, one or more SAM molecules attached to the one or more surfaces of the medical device, and one or more therapeutic agents attached to the one or more self-assembled monolayer molecules. Also disclosed are medical devices comprising one or more surfaces, one or more self-assembled monolayer molecules attached to the one or more surfaces of the medical device, one or more linkers comprising a first functional group and a second functional group, the first functional group attached to the self-assembled monolayer molecule and a therapeutic agent attached to the second functional group. The therapeutic agent may be attached to the SAM molecule via a linker. The present invention also concerns methods of administering a therapeutic agent to a subject, comprising contacting the subject with one of the medical devices set forth herein.
• METHOD OF PRODUCING A POLYMER PART AND POLYMER PART
  申请人：Sony DADC Austria AG

  公开号：US20140309375A1

  公开（公告）日：2014-10-16

  A method of producing a polymer part comprising the following steps: (a) incorporating a hydrophobic small molecule into the polymer before, during or after manufacture of the polymer part, the hydrophobic small molecule and the polymer being essentially inert to one another; and (b) annealing the polymer part to induce migration of the hydrophobic small molecules to a surface of the polymer part to provide that surface with a specified degree of hydrophobicity defined by the combination of the polymer and the hydrophobic small molecule; is described. Polymer parts made according to the method are also described.