But-2-enedioic acid;ethane-1,2-diamine | 112915-82-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: But-2-enedioic acid;ethane-1,2-diamine
• 英文别名: but-2-enedioic acid;ethane-1,2-diamine
• CAS: 112915-82-9
• 化学式: C6H12N2O4
• 分子量: 176.17
• InChiKey: BZZLZISANHDNBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.38
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  127
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Alkynyl multi-arm polyethylene glycol derivative
  申请人：JENKEM TECHNOLOGY CO., LTD. (BEIJING)

  公开号：US10280259B2

  公开（公告）日：2019-05-07

  The present invention provides an alkynyl multi-arm polyethylene glycol derivative having a structure of a general formula I or general formula X VIII. In the derivative, X1, X2, X3 and X4 are linking groups, F1, F2, F3 and F4 are end groups, the end groups may be the same or may also be different, and are selected from: hydroxy, carboxyl, ester group, amino, alkynyl or the like, at least one of the end groups is alkynyl, and PEG is the same or different —(CH2CH2O)m—, wherein m is an integer ranging from 3 to 250, and l is an integer greater than or equal to 1. The multi-arm polyethylene glycol derivatives have stronger application flexibility, and have good application prospect in aspects such as organic synthesis, medicine synthesis and medical instruments.

  本发明提供了一种具有通式 I 或通式 X VIII 结构的炔基多臂聚乙二醇衍生物。该衍生物中，X1、X2、X3和X4为连接基团，F1、F2、F3和F4为端基团，端基团可以相同也可以不同，选自：羟基、羧基、酯基、氨基、炔基等，其中至少一个端基团为炔基，PEG为相同或不同的-(CH2CH2O)m-，其中m为3～250的整数，l为大于等于1的整数。多臂聚乙二醇衍生物具有更强的应用灵活性，在有机合成、医药合成、医疗器械等方面具有良好的应用前景。
• ALKYNYL MULTI-ARM POLYETHYLENE GLYCOL DERIVATIVE
  申请人：JENKEM TECHNOLOGY CO., LTD. (BEIJING)

  公开号：US20160271267A1

  公开（公告）日：2016-09-22

  The present invention provides an alkynyl multi-arm polyethylene glycol derivative having a structure of a general formula I or general formula X VIII. In the derivative, X1, X2, X3 and X4 are linking groups, F1, F2, F3 and F4 are end groups, the end groups may be the same or may also be different, and are selected from: hydroxy, carboxyl, ester group, amino, alkynyl or the like, at least one of the end groups is alkynyl, and PEG is the same or different —(CH 2 CH 2 O) m —, wherein m is an integer ranging from 3 to 250, and 1 is an integer greater than or equal to 1. The multi-arm polyethylene glycol derivatives have stronger application flexibility, and have good application prospect in aspects such as organic synthesis, medicine synthesis and medical instruments.