7-methyl-3-octyn-1,5-diol | 105750-99-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-methyl-3-octyn-1,5-diol
• 英文别名: 7-Methyloct-3-yne-1,5-diol；7-methyloct-3-yne-1,5-diol
• CAS: 105750-99-0
• 化学式: C₉H₁₆O₂
• 分子量: 156.225
• InChiKey: IMMYXUALWCPKCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-Octyn-4-ol, 2-methyl-8-[(tetrahydro-2H-pyran-2-yl)oxy]- 生成 7-methyl-3-octyn-1,5-diol
  参考文献：
  名称：

  Synthesis of a Protected Acetylene Dipeptide Isostere

  摘要：

  AbstractA racemic dipeptide analogue of Leu‐Gly in which the peptide bond is replaced by a carbon‐carbon triple bond has been prepared. Key steps are the use of a Mitsunobu reaction to introduce a phtaloyl‐protected aminogroup and subsequent Jones oxidation of a primary alcohol to the carboxylic acid.

  DOI：

  10.1002/bscb.19860950209

文献信息

• Synthesis of a Protected Acetylene Dipeptide Isostere
  作者：M. van Marsenille、C. Gysen、D. Tourwé、G. van Binst

  DOI：10.1002/bscb.19860950209

  日期：——

  AbstractA racemic dipeptide analogue of Leu‐Gly in which the peptide bond is replaced by a carbon‐carbon triple bond has been prepared. Key steps are the use of a Mitsunobu reaction to introduce a phtaloyl‐protected aminogroup and subsequent Jones oxidation of a primary alcohol to the carboxylic acid.