2-(2'-Methylphenyl)-3-methylphenol | 15067-25-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2'-Methylphenyl)-3-methylphenol
• 英文别名: 6-Hydroxy-2,2'-dimethylbiphenyl；2-(o-Tolyl)-3-methylphenol；3-Methyl-2-(2-methylphenyl)phenol
• CAS: 15067-25-1
• 化学式: C₁₄H₁₄O
• 分子量: 198.265
• InChiKey: DSCAMNWLXLBTND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  6-Methoxy-2,2'-dimethylbiphenyl 在 氢溴酸 、 溶剂黄146 作用下， 生成 2-(2'-Methylphenyl)-3-methylphenol
  参考文献：
  名称：

  Hall,D.M.; Insole,J.M., Journal of the Chemical Society. Perkin transactions II, 1972, p. 1164 - 1168

  摘要：

  DOI：

文献信息

• 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them
  申请人：SYNTEX (U.S.A.) INC.

  公开号：EP0157652A1

  公开（公告）日：1985-10-09

  Compounds useful for treating inflammation, swelling and associated pain, and psoriasis, represented by the formula: and the pharmaceutically acceptable acid addition salts thereof, wherein: a is an integer of 0-3; b is an integer of 0-2; n is an integer of 3-12; each X and each Y are independently-halo, -R1, -alkoxy, or-phenyl; and B is selected from: and in which R' and R2 are independently H, alkyl or cycloalkyl; R3 is H, alkyl or -CH2CH2OH; and m is an integer of 3-8. Novel compounds are those wherein n is at least 6 if both a and b are 0.

  用于治疗炎症、肿胀及相关疼痛和牛皮癣的化合物，由式：及其药学上可接受的酸加成盐表示，其中：a 是 0-3 的整数；b 是 0-2 的整数；n 是 3-12 的整数；每个 X 和每个 Y 独立地是卤素、-R1、-烷氧基或苯基；B 选自：且其中 R' 和 R2 独立地是 H、烷基或环烷基；R3 是 H、烷基或-CH2CH2OH；且 m 是 3-8 的整数。 新型化合物是指如果 a 和 b 均为 0，则 n 至少为 6 的化合物。
• 10.1021/acs.orglett.4c01308
  作者：Klischan, Moritz K. T.、David, Céline、Grudzinski, Daniel、Frey, Wolfgang、Stork, Björn、Pietruszka, Jörg

  DOI：10.1021/acs.orglett.4c01308

  日期：——

  The application of cyclic diaryliodonium salts in the synthesis of bioactive natural product analogues was demonstrated. Axially chiral biaryls were obtained via the enantioselective ring opening of cyclic diaryliodonium salts. Regioselective borylation was key in accessing both enantiomers of a biphenol key intermediate in eight steps overall. 8,8″-Amino biflavones were synthesized, their bioactivity

  展示了环状二芳基碘鎓盐在生物活性天然产物类似物合成中的应用。轴向手性联芳基是通过环状二芳基碘鎓盐的对映选择性开环获得的。区域选择性硼化是通过八个步骤获得联苯酚关键中间体的两种对映体的关键。合成了 8,8”-氨基双黄酮，分析了其生物活性，并鉴定了优异构体。探讨了结构-活性关系。
• [EN] FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME<br/>[FR] COMPOSITION DE POLY(PHENYLENE ETHER) IGNIFUGEE ET SON PROCEDE DE FABRICATION
  申请人：GEN ELECTRIC

  公开号：WO2002018485A1

  公开（公告）日：2002-03-07

  Polyphenylene ether (PPE) compositions with good fire and flame retardant characteristics utilize lower levels of organophosphate fire-retardant, and therefore do not suffer from the drawbacks of previously known fire- and flame-retardant PPE compositions. The compositions include (a) a polymer component containing a polyphenylene ether; (b) glass or carbon reinforcing fibers in an amount sufficient to increase the modulus and strength of the polymer component; (c) a fire retardant component which is preferably an organophosphate fire retardant; (d) a mineral component in an amount effective to enhance the flame-retardant characteristics of the composition. Other conventional additives utilized in formulation of PPE may be included. The composition is made by mixing the ingredients and compounding into a composition which is suitable for injection molding. This composition can be used in the manufacture of injection molded articles such as electronic components, including television internals such as deflection yokes; printer chassis and plastic pallets.
• Hall,D.M.; Insole,J.M., Journal of the Chemical Society. Perkin transactions II, 1972, p. 1164 - 1168
  作者：Hall,D.M.、Insole,J.M.

  DOI：——

  日期：——