isopropenyl 4-methoxyphenyl sulfide | 145146-17-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: isopropenyl 4-methoxyphenyl sulfide
• 英文别名: 1-Methoxy-4-prop-1-en-2-ylsulfanylbenzene
• CAS: 145146-17-4
• 化学式: C₁₀H₁₂OS
• 分子量: 180.271
• InChiKey: DHGXONLRYJXQOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  34.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  isopropenyl 4-methoxyphenyl sulfide 、 3-[(E)-3-(methoxycarbonyl)-propenoyl]-oxazolidin-2-one 以14%的产率得到
  参考文献：
  名称：

  Narasaka Koichi, Hayashi Yujiro, Shimadzu Hideshi, Niihata Shigeo, J. Amer. Chem. Soc., 114 (1992) N 23, S 8869-8885

  摘要：

  DOI：
• 作为产物：
  描述：

  isopropyl-p-anisyl sulfoxide 在 乙基溴化镁 、 异丙胺 作用下， 以66%的产率得到isopropenyl 4-methoxyphenyl sulfide
  参考文献：
  名称：

  Synthesis of 1-(1-Arylsulfanylalkyl)indoles and 2,2-Bis[1-(1-arylsulfanylalkyl)indol-3-yl]propanes by Acid-Catalyzed Reactions of Indoles with Aryl Vinyl Sulfides

  摘要：

  We report a facile synthesis of 1-(1-arylsulfanylalkyl)indoles and 2,2-bis[1-(1-arylsulfanylalkyl)indol-3-yl]propanes under mild conditions. Thus, treatment of 3-substituted indoles with aryl vinyl sulfides in dichloromethane at room temperature in the presence of a catalytic amount of (+/-)-camphor-10-sulfonic acid yields the former indole derivatives in moderate to fair yields. 3-Nonsubstituted indoles can be transformed into the latter indole derivatives in satisfactory yields on treatment with excess aryl vinyl sulfides in the presence of a catalytic amount of the acid under similar conditions.

  DOI：

  10.3987/com-09-11867

文献信息

• Asymmetric [2 + 2] cycloaddition reaction catalyzed by a chiral titanium reagent
  作者：Koichi Narasaka、Yujiro Hayashi、Hideshi Shimadzu、Shigeo Niihata

  DOI：10.1021/ja00049a020

  日期：1992.11

  In the presence of certain Lewis acids, alkenes containing an alkylthio group (for example, ketene dithioacetals, alkenyl sulfides, alkynyl sulfides, and allenyl sulfides) react with electron deficient olefins to give the corresponding cyclobutane, cyclobutene, or methylene cyclobutane derivatives. By employing a chiral titanium catalyst generated in situ from dichlorodiisopropoxytitanium and a tartrate-derived chiral diol, the [2 + 2] cycloaddition reaction proceeds with high enantioselectivity.