Diiodhistidin | 13726-59-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Diiodhistidin
• 英文别名: Dijodhistidin；2,5-Diiod-histidin；2,5-diiodo-histidine；NoName_3617；2-azaniumyl-3-(2,4-diiodo-1H-imidazol-5-yl)propanoate
• CAS: 13726-59-5
• 化学式: C₆H₇I₂N₃O₂
• 分子量: 406.949
• InChiKey: ZMELUTBTYDGWOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  92
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• MULTIMERIC PEPTIDE
  申请人：Bionor Immuno AS

  公开号：EP3338798A1

  公开（公告）日：2018-06-27

  The present invention relates to peptides and methods for inducing an immune response in a subject against an antigen and for treatment, diagnosis and prognosis of infections or autoimmune diseases including infections with HCV, HIV, CMV and Flu. The invention further relates to methods for identifying and providing peptides useful for the treatment and diagnosis.

  本发明涉及诱导受试者对抗原产生免疫应答的肽和方法，以及用于治疗、诊断和预后感染或自身免疫性疾病（包括感染HCV、HIV、CMV和流感）的肽和方法。本发明还涉及鉴定和提供用于治疗和诊断的多肽的方法。
• Synthesis of hydantoin containing peptide products
  申请人：SANOFI-AVENTIS DEUTSCHLAND GMBH

  公开号：US10087221B2

  公开（公告）日：2018-10-02

  The present invention relates to a method of synthesizing a peptide product comprising at least one hydantoin group. The peptide product may be used as a reference material for the quality control of pharmaceutical peptides, particularly for the quality control of exendin peptides. Further, the invention relates to hydantoin building blocks, a method for manufacturing such building blocks and their use for the synthesis of peptide products.

  本发明涉及一种合成包含至少一个海因基团的多肽产品的方法。该多肽产品可用作药物多肽质量控制的参考材料，特别是用于外激素多肽的质量控制。此外，本发明还涉及海因砌块、制造这种砌块的方法及其用于合成肽产品的用途。
• Dimeric scaffold peptides comprising HIV-1 GP120 and GP41 epitopes
  申请人：BIONOR IMMUNO AS

  公开号：US10124059B2

  公开（公告）日：2018-11-13

  The present invention relates to novel peptides and methods for inducing an immune response in a subject against an antigen and for treatment, diagnosis and prognosis of infections or autoimmune diseases including infections with HCV, HIV, CMV and Flu. The invention further relates to methods for identifying and providing peptides useful for the treatment and diagnosis.

  本发明涉及用于诱导受试者对抗原产生免疫应答的新型多肽和方法，以及用于感染或自身免疫性疾病（包括HCV、HIV、CMV和流感感染）的治疗、诊断和预后的新型多肽和方法。本发明还涉及鉴定和提供用于治疗和诊断的多肽的方法。
• Peptides derived from viral proteins for use as immunogens and dosage reactants
  申请人：Bionor Immuno AS

  公开号：US10501499B2

  公开（公告）日：2019-12-10

  The present invention relates to novel peptides and methods for treatment, diagnosis and prognosis of virus infections including infections with HCV, HIV, HPV, CMV and Influenza. The invention further relates to methods for identifying and providing peptides useful for the treatment and diagnosis.

  本发明涉及治疗、诊断和预后病毒感染（包括感染 HCV、HIV、HPV、CMV 和流感）的新型多肽和方法。本发明还涉及鉴定和提供用于治疗和诊断的多肽的方法。
• COMPOUNDS MODULATORS OF VEGF ACTIVITY AND USES THEREOF
  申请人：Advanced Accelerator Applications S.A.

  公开号：EP2456784A1

  公开（公告）日：2012-05-30