N-(2-hydroxyethyl)-2-(3-pentadecylphenoxy) acetamide | 861891-72-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-(2-hydroxyethyl)-2-(3-pentadecylphenoxy) acetamide
• 英文别名: 3-N-pentadecyl-ethanolamide；PDP-EA；N-(2-hydroxyethyl)-2-(3-pentadecylphenoxy)acetamide
• CAS: 861891-72-7
• 化学式: C₂₅H₄₃NO₃
• 分子量: 405.621
• InChiKey: BIOVSNWTCKRADD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  29
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE
  申请人：Research Foundation of the City University of New York

  公开号：US20150359218A1

  公开（公告）日：2015-12-17

  A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacylethanolamide that causes the enhanced activity. The enhanced activity can have numerous effects on biological organisms including, for example, enhancing the growth of certain seedlings. The subject matter disclosed herein relates to enhancers of amidohydrolase activity.
• US9474271B2
  申请人：——

  公开号：US9474271B2

  公开（公告）日：2016-10-25
• US9849101B2
  申请人：——

  公开号：US9849101B2

  公开（公告）日：2017-12-26
• [EN] LIPOSOMAL FORMULATIONS OF THE ANTINEOPLASTIC AGENTS<br/>[FR] FORMULATIONS LIPOSOMALES D'AGENTS ANTINEOPLASIQUES
  申请人：INST FARMACEUTYCZNY

  公开号：WO2005072776A2

  公开（公告）日：2005-08-11

  The invention relates to the liposomal formulation of an antineoplastic agent encapsulated in the liposomal vesicles which are the composition of lipid components, wherein the ratio of a therapeutically active agent to the lipid components is between about 1:10 and about 1:30 (w/w). The composition of lipid components contains at least one phospholipid derivative and at least one alkylphenol derivative presented by a general formula (I) , wherein: n is an integer 1 - 17; m is an integer 0-15; X is -C=O, -0- or a bond; Y is a group of formula -NR2R3, a monosaccharide moiety or a bond; Z is H, -0-, -N-, -OR4, -NR4 or a monosaccharide moiety, R5 is H or COOH.