cis-[Pt(NO3)2(PMePh2)2] | 68879-09-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: cis-[Pt(NO3)2(PMePh2)2]
• 英文别名: cis-Pt(NO3)2(PMePh2)；cis-[(PMePh2)2Pt(ONO2)2]；cis-(PPh2Me)2Pt(ONO2)2；cis-Pt(PMePh2)2(NO3)2
• CAS: 68879-09-4
• 化学式: C₂₆H₂₆N₂O₆P₂Pt
• 分子量: 719.53
• InChiKey: DPTJMQHMUAILBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  1-甲基胞嘧啶 、 cis-[Pt(NO3)2(PMePh2)2] 以 N,N-二甲基甲酰胺 为溶剂， 以65%的产率得到cis-[(PPh2Me)2Pt(1-methylcytosine)2](NO3)2
  参考文献：
  名称：

  膦配体对铂（II）络合物中模型核碱基1-甲基胞嘧啶和9-甲基鸟嘌呤单加合物的稳定作用。

  摘要：

  将1-甲基胞嘧啶（1-MeCy）或9-甲基鸟嘌呤（9-MeGu）以1：1的摩尔比添加到顺式（PPh3）2P（ONO2）2（1a）的溶液中，得到一加合物顺式-[（（PPh3）2Pt（1-MeCy）（ONO2）] NO3（2a）和顺式-[（PPh3）2Pt（9-MeGu）（ONO2）] NO3（3a）和仅少量的双加合物顺式-[ （PPh3）2Pt（1-MeCy）2]（NO3）2（4a）和cis-[（PPh3）2Pt（9-MeGu）2]（NO3）2（5a）。对2a和3a的X射线结构测定表明PPh3苯基之一与N7配位的鸟嘌呤碱基的嘧啶N3镀的胞嘧啶或咪唑部分之间有很强的pi-pi堆积相互作用。在单加合物中添加另外等价的核苷碱基定量地形成了已被分离为纯化合物4a和5a的双加合物。在相同的实验条件下 dinitrato类似物顺式[[（PMePh2）2Pt（ONO2）2]（1b）形成单加合物2b和3b，

  DOI：

  10.1021/ic7020319
• 作为产物：
  描述：

  cis-[((PMePh2)2Pt(ONO2))2(9-methyladenine)](NO3)2 以 乙醇 、 二氯甲烷 为溶剂， 生成 cis-[Pt(NO3)2(PMePh2)2]
  参考文献：
  名称：

  Complexes of Platinum(II) Containing Neutral and Deprotonated 9-Methyladenine. Synthesis, X-ray Structures, and NMR Studies on the Cyclic Trimer cis-[L₂Pt{9-MeAd(−H)}]₃(NO₃)₃ and the Dinuclear cis-[L₂Pt(ONO₂){9-MeAd(−H)}PtL₂](NO₃)₂ (L = PMePh₂)

  摘要：

  The dinuclear hydroxo complex cis-[L2Pt(mu-OH)](2)(NO3)(2) (L = PMePh2, 1), in CH2Cl2, CH3CN, or DMF solution, deprotonates the NH2 group of 9-methyladenine (9-MeAd) to give the complex cis-[L2Pt{9-MeAd(-H)}](3)(NO3)(3), 2, which was isolated in good yield. The X-ray structure shows that the nucleobase binds symmetrically the metal centers through the N(1),N(6) atoms forming a cyclic trimer with Pt...Pt distances in the range 5.202(1)-5.382(1) Angstrom. Dissolution of 2 in DMSO or DMF determines the partial (or total) dissociation of the cyclic structure to form several fragments. A multinuclear NMR analysis of the resulting mixture supports the presence of the mononuclear species cis-[L2Pt{9-MeAd(-H)}](+), 3, in which the deprotonated nucleobase chelates the metal center with the N(6),N(7) atoms. Addition of a stoichiometric amount of the nitrato complex cis-[L2Pt(ONO2)(2)] (L = PMePh2, 4) to a DMSO or DMF solution of 2 affords quantitatively the diplatinated compound cis-[L2Pt(NO2){9-MeAd(-H)}-PtL2](NO3)(2), 5. The single-crystal X-ray analysis shows that the adenine behaves as a tridentate ligand bridging two cis-L2Pt units at the N(1) and N(6),N(7) sites, respectively [Pt(l)-N(l) = 2.109(5) Angstrom, Pt(2)-N(6) = 2.095(7) Angstrom, Pt(2)-N(7) = 2.126(7) Angstrom]. The N(1)-bonded metal center completes the coordination sphere through an oxygen atom of a nitrate group, and its coordination plane is arranged orthogonally with respect the second one. The Pt-O distance [2.109(5) Angstrom] is similar to those found in the nitrato complex 4 [2.110 Angstrom, average]. The related complex cis-[{L2Pt(ONO2)}(2)(9-MeAd)](NO3)(2), 6, containing the neutral adenine platinated at the N(1),N(7) atoms, was isolated and its stability in solution investigated by NMR spectroscopy, In DMSO, 6 undergoes decomposition forming a mixture of the species 4, 5, and the adenine mono- and bis-adducts cis-[L2Pt(9-MeAd)(DMSO)](2+), 7, and cis-[L2Pt(9-MeAd)(2)](2+), 8, respectively. This last complex, quantitatively formed upon addition of 9-MeAd (Pt/adenine 1:2) to the mixture, was also isolated and characterized.

  DOI：

  10.1021/ic034406z

文献信息

• Reactions of hexafluorobut-2-yne with alkylgold(<scp>I</scp>) complexes. Properties of intermediate binuclear gold(<scp>I</scp>)–gold(<scp>III</scp>) complexes
  作者：Antony Johnson、Richard J. Puddephatt

  DOI：10.1039/dt9780000980

  日期：——

  Reactions of alkylgold(I) complexes [AuRL](R = Me, L = PMe3, PMe2Ph, or PMePh2; R = Et, L = PMePh2) with hexafluorobut-2-yne give first the mixed-oxidation-state complexes [LAu(F3C)CC(CF3)}AuR2L], which react further to give either the binuclear gold(I) complexes [LAu(F3C)CC(CF3)}AuL] or the products of cis in-sertion of the alkyne into the original Au–C bond, [AuL(F3C) CCR (CF3)}]. The course of

  烷基金（I）配合物[AuRL]（R = Me，L = PMe 3，PMe 2 Ph或PMePh 2 ; R = Et，L = PMePh 2）与六氟丁-2-炔的反应首先产生混合氧化-态络合物[LAu （F 3 C）C C（CF 3）} AuR 2 L]，它们进一步反应生成双核金（I）络合物[LAu （F 3 C）CC C（CF 3）} ] AUL或产物顺在-插入可以炔成原始的Au-C键，[AUL （F的3 ç）C CR（CF 3）}]。此后续反应的过程取决于L和R的性质以及溶剂，并且已经研究了反应机理。氯化氢与[LAu （F 3 C）CC C（CF 3）} AuMe 2 L]（L = PMe 3）反应，裂解乙烯基金（I）键，得到[AuCIL]和[AuMe 2 L （F 3 C）ç CH（CF 3）}]，而金属卤化物的HgCl 2，[PTX 2（PMePh 2）2 ]}最初反应以
• Selectivity in reactions of alkyl-aryl-transition-metal complexes with electrophiles
  作者：Jaafar K. Jawad、Richard J. Puddephatt、Maria A. Stalteri

  DOI：10.1021/ic00131a061

  日期：1982.1
• A coordination polymer formed by cis-[(PMePh2)2Pt(NO3)2] and 2,5-bis(4-pyridyl)-1,3,4-thiadiazole
  作者：Renato Ettorre、Bruno Longato、Ennio Zangrando

  DOI：10.1016/j.ica.2008.01.038

  日期：2008.6

  The 1:1 adduct formed from cis-[(PMePh(2))(2)Pt(NO(3))(2)] and 2,5-bis(4-pyridyl)-1,3,4-thiadiazole (bpytdz) in chloroform crystallizes out as a 1D coordination polymer built up of cis-( PMePh2)(2)Pt units connected by the bpytdz ligand, an unusual self-assembly for a complex formed from a (phosphine)(2)Pt(II) entity and a N, N linker. (c) 2008 Elsevier B. V. All rights reserved.