(4-{3-[3-(4-dimethylaminophenyl)-1-heptylureido]phenylsulphanyl}phenyl)acetic acid | 735313-61-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (4-{3-[3-(4-dimethylaminophenyl)-1-heptylureido]phenylsulphanyl}phenyl)acetic acid
• 英文别名: 2-[4-[3-[[4-(Dimethylamino)phenyl]carbamoyl-heptylamino]phenyl]sulfanylphenyl]acetic acid
• CAS: 735313-61-8
• 化学式: C₃₀H₃₇N₃O₃S
• 分子量: 519.708
• InChiKey: KTAGIBCPWHJMHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  37
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  98.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS<br/>[FR] COMPOSES MODULATEURS DES RECEPTEURS DU TYPE PPAR ET LEUR UTILISATION DANS DES PREPARATIONS PHARMACEUTIQUES ET COSMETIQUES
  申请人：GALDERMA RES & DEV

  公开号：WO2004071504A1

  公开（公告）日：2004-08-26

  The invention relates to novel compounds which correspond to the general formula (I), their method of preparation, and their use in pharmaceutical compositions intended for use in human or veterinary medicine (in dermatology and in the field of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or in cosmetic compositions.

  本发明涉及与通式（I）相对应的新化合物，其制备方法以及它们在制备用于人类或兽医药物（在皮肤病学以及心血管疾病、免疫疾病和/或与脂质代谢有关的疾病领域）或化妆品中的应用。
• Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof
  申请人：Diaz Philippe

  公开号：US20060052627A1

  公开（公告）日：2006-03-09

  Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.

  调节PPAR型受体的新化合物具有以下一般式(I)，并制成适合于人类或兽医药学（在皮肤科以及心血管疾病、免疫疾病和/或与脂质代谢有关的领域）的药物组合物，或制成化妆品组合物。
• COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
  申请人：Galderma Research & Development, S.N.C.

  公开号：EP1596853A1

  公开（公告）日：2005-11-23