Synthesis and Antimicrobial Activities of Novel Biologically Active Heterocycles: 10H-Phenothiazines, Their Ribofuranosides, and Sulfone Derivatives
作者:Yogesh Dixit、Rahul Dixit、Naveen Gautam、D. C. Gautam
DOI:10.1080/15257770903362206
日期:2009.12.7
This article deals with the synthesis and antimicrobial activity of a series of novel substituted 10H-phenothiazines, their ribofuranosides, and sulfone derivatives. 10H-Phenothiazines were prepared by Smiles rearrangement. These prepared phenothiazines were used as the base to prepare ribofuranosides by treatment with sugar (1-O-acetyl-2,3,5-tri-O-benzoylribofuranose). Sulfone derivatives were prepared
本文讨论了一系列新型取代的10H-吩噻嗪,它们的呋喃核糖苷和砜衍生物的合成和抑菌活性。通过Smiles重排制备10 H-吩噻嗪。这些制备的吩噻嗪用作碱,通过用糖(1-O-乙酰基-2,3,5-三-O-苯甲酰基核呋喃糖)处理来制备呋喃核糖苷。通过氧化10H-吩噻嗪制备砜衍生物。通过元素分析和光谱数据确定了合成化合物的结构。