Conformational analysis of -(1-methoxycarbonylethyl)-Δ4-thiazoline-2-thiones by temperature-dependent circular dichroism and NMR spectroscopy and by molecular mechanics calculations
作者:Jan Roschester、Jan Sandström
DOI:10.1016/s0040-4020(01)81088-7
日期:1989.1
The conformations of seven -(1-methoxycarbonylethyl)-Δ4-thiazoline-2-thiones with configuration of the chiral rotor have been studied by temperature-dependent NMR and CD spectroscopy, and for four compounds by molecularmechanicscalculations. The syn-anti equilibria previously reported have been confirmed, and other conformational processes, involving low energy barriers, have been shown to be operating