3-Ethyl-1-methylpiperazin-2-one | 1214796-54-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-Ethyl-1-methylpiperazin-2-one
• CAS: 1214796-54-9
• 化学式: C₇H₁₄N₂O
• 分子量: 142.2
• InChiKey: TWMDADGNNMFROF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PYRAZOLO[4,3-D]PYRIMIDINE COMPOUNDS AS ALK2 ABD/OR FGFR MODULATORS
  申请人：Incyte Corporation

  公开号：EP3856348A1

  公开（公告）日：2021-08-04
• [EN] PYRAZOLO[4,3-D]PYRIMIDINE COMPOUNDS AS ALK2 ABD/OR FGFR MODULATORS<br/>[FR] COMPOSÉS PYRAZOLO[4,3-D]PYRIMIDINE EN TANT QUE MODULATEURS DES ALK2 ET/OU FGFR
  申请人：INCYTE CORP

  公开号：WO2020068729A1

  公开（公告）日：2020-04-02

  Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting ALK2 activity and/or FGFR activity, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with ALK2 activity and/or FGFR activity, such as cancer.