24-methyl-8-lanosten-3β-ol | 16711-61-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 24-methyl-8-lanosten-3β-ol
• 英文别名: 24ξH-eburic-8-en-3β-ol；(3S,5R,10S,13R,14R,17R)-17-[(2R)-5,6-dimethylheptan-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• CAS: 16711-61-8
• 化学式: C₃₁H₅₄O
• 分子量: 442.769
• InChiKey: ASIHPHAOMMSKTQ-HGUGANRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.6
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  24-methyl-8-lanosten-3β-ol 生成 4alpha,14-Dimethyl-5alpha-ergosta-8,24(28)-dien-3beta-ol
  参考文献：
  名称：

  KATO, TOSHIRO, J. PESTIC. SCI., 1982, 7, N 3, 427-437

  摘要：

  DOI：
• 作为产物：
  描述：

  3β-acetoxy-24ξH-eburic-8-en-21-oic acid 在 氢氧化钾 、 Pd-BaSO₄ 、 氯化亚砜 、 邻二甲苯 、 一水合肼 、 二乙二醇 作用下， 反应 2.0h， 生成 24-methyl-8-lanosten-3β-ol
  参考文献：
  名称：

  Holker et al., Journal of the Chemical Society, 1953, p. 2422,2427

  摘要：

  DOI：

文献信息

• Synthesis of a 24-Epimeric Mixture of 4α,14α,24-Trimethyl-9(11)-cholesten-3-one
  作者：Masahiko Yamashita、Misuzu Naora、Tatsushi Murae、Takahiko Tsuyuki、Takeyoshi Takahashi

  DOI：10.1246/bcsj.60.1383

  日期：1987.4

  A 24-epimeric mixture of 4α,14α,24-trimethyl-9(11)-cholesten-3-one was synthesized from lanosterol through 4α,14α,24-trimethyl-8-cholesten-3β-ol and 4α,14α,24-trimethyl-7,11-dioxocholestan-3β-yl acetate as key intermediates.

  一种24-表异构体混合物4α,14α,24-三甲基-9(11)-胆甾烯-3-酮是通过4α,14α,24-三甲基-8-胆甾烯-3β-醇和4α,14α,24-三甲基-7,11-二氧胆甾烯-3β-醋酸酯作为关键中间体，从兰斯特醇合成的。
• 195. Eburicoic acid
  作者：F. N. Lahey、P. H. A. Strasser

  DOI：10.1039/jr9510000873

  日期：——
• THERAPEUTIC USES FOR PLANTS OF THE CAPSICUM GENUS
  申请人：Rezai-Fard, Ali

  公开号：EP2456453A1

  公开（公告）日：2012-05-30
• Therapeutic Uses for Plants of the Capsicum Genus
  申请人：Rezai-Fard Ali

  公开号：US20120195988A1

  公开（公告）日：2012-08-02

  A saponin or a sapogenin, or a saponin or sapogenin derivative, from a plant of the capsicum genus for use in the treatment of a disease other than eczema and dermatitis. A process for preparing a plant of the capsicum genus, extracts, or seeds thereof for use as a medicament suitable for the treatment of diseases other than skin conditions which process comprises storing the plant, extracts or seeds thereof at a temperature of 20° C. or below.
• [EN] THERAPEUTIC USES FOR PLANTS OF THE CAPSICUM GENUS<br/>[FR] UTILISATIONS THÉRAPEUTIQUES DE PLANTES DU GENRE CAPSICUM
  申请人：REZAI-FARD ALI

  公开号：WO2011010090A1

  公开（公告）日：2011-01-27

  A saponin or a sapogenin, or a saponin or sapogenin derivative, from a plant of the capsicum genus for use in the treatment of a disease other than eczema and dermatitis. A process for preparing a plant of the capsicum genus, extracts, or seeds thereof for use as a medicament suitable for the treatment of diseases other than skin conditions which process comprises storing the plant, extracts or seeds thereof at a temperature of 2O°C or below.