Nampamp-ile-hse lactone | 149786-89-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Nampamp-ile-hse lactone
• 英文别名: 2-[[2-[(2-amino-3-sulfanylpropyl)amino]-3-methylpentyl]amino]-3-methyl-N-(2-oxooxolan-3-yl)pentanamide
• CAS: 149786-89-0
• 化学式: C₁₉H₃₈N₄O₃S
• 分子量: 402.6
• InChiKey: SSUQYMRCKYEGEO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  27
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  107
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• IMPROVEMENTS RELATING TO THE PREPARATION OF PRODRUGS
  申请人：CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED

  公开号：EP0711177B1

  公开（公告）日：2007-05-09
• COMPOSITION AND METHOD FOR TREATING CANCER
  申请人：CELLWORKS GROUP, INC.

  公开号：US20160058751A1

  公开（公告）日：2016-03-03

  The present disclosure relates to a pharmaceutical composition and a kit to treat cancer. The disclosure provides a combination of compounds for use in the treatment of cancer. The disclosure further provides a process of preparing the composition and a method of treating a cancer associated with a RAS mutation or a RAS mutation along with any other mutation.
• [EN] COMPOSITION AND METHOD FOR TREATING CANCER<br/>[FR] COMPOSITION ET MÉTHODE POUR LE TRAITEMENT DU CANCER
  申请人：CELLWORKS RES INDIA PVT LTD

  公开号：WO2014160729A1

  公开（公告）日：2014-10-02

  The present disclosure relates to a pharmaceutical composition and a kit to treat cancer. The disclosure provides a combination of compounds for use in the treatment of cancer. The disclosure further provides a process of preparing the composition and a method of treating a cancer associated with a RAS mutation or a RAS mutation along with any other mutation.