申请人:DIONEX CORPORATION
公开号:US20160122368A1
公开(公告)日:2016-05-05
A chromatographic material comprising a zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II:
wherein
R
1
, R
2
, R
3
are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group;
L
1
, L
2
and L
3
are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L
1
, L
2
and L
3
;
X is an O atom, S atom, amide group or sulfonamide group;
n is 0 or 1;
R
4
, R
5
are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; and
R
f
is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.