(R)-3-aminopentadecanoic acid | 1351929-82-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (R)-3-aminopentadecanoic acid
• CAS: 1351929-82-2
• 化学式: C₁₅H₃₁NO₂
• 分子量: 257.417
• InChiKey: BVWPLAHBHYVQQY-CQSZACIVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18.0
• 可旋转键数：
  13.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  63.32
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  (R)-tert-butyl 3-[(S)-2-hydroxy-1-phenylethylamino]pentadecanoate 在 palladium 10% on activated carbon 、 甲酸铵 、 三氟乙酸 作用下， 以 甲醇 为溶剂， 反应 7.0h， 生成 (R)-3-aminopentadecanoic acid
  参考文献：
  名称：

  Cyclodysidins A–D, cyclic lipopeptides from the marine sponge-derived Streptomyces strain RV15

  摘要：

  Four new cyclic lipopeptides, cyclo-(AFA-Ser-Gln-Asn-Tyr-Asn-Ser-Thr), named cyclodysidins A-D, were isolated from the broth culture of Streptomyces strain RV15 associated with the marine sponge Dysidea tupha. The sequences of the amino acid building blocks in the compounds and their structures were determined by 1D- and 2D-NMR techniques and CID-MS/MS experiments. The absolute configurations of all alpha-amino acids were determined by HPLC analysis after derivatization with Marfey's reagent and comparison with commercially available reference samples, while those two of the beta-amino fatty acids were determined by using racemic and enantiopure reference samples synthetically prepared. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.051