申请人:Sumitomo Chemical Company, Limited
公开号:EP2090358A1
公开(公告)日:2009-08-19
It is possible to perform microencapsulation of a bioactive substance having a solid form at ordinary temperature in a predetermined wall thickness and particle size without the need of dissolving the solid biologically active substance in any solvent by a method for producing a microcapsule, comprising: heating an aqueous dispersion comprising a dispersion stabilizer, an ionic surfactant, the solid biologically active substance, a polymerization initiator and a radical-polymerizable monomer subjected to ultrasonic irradiation. Therefore, the method enables to design a desired particle readily and it is useful for the microencapsulation.
通过一种生产微胶囊的方法,可以在常温下以预定壁厚和粒径对具有固体形态的生物活性物质进行微胶囊化,而无需将固体生物活性物质溶解在任何溶剂中,该方法包括:加热由分散稳定剂、离子型表面活性剂、固体生物活性物质、聚合引发剂和可自由基聚合单体组成的水性分散体,并对其进行超声波辐照。因此,该方法可以很容易地设计出所需的颗粒,并可用于微胶囊化。