4-[(3,5-dinitrothiophen-2-yl)diazenyl]-N,N-diethyl-3-methylaniline | 102301-05-3

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: 4-[(3,5-dinitrothiophen-2-yl)diazenyl]-N,N-diethyl-3-methylaniline
• CAS: 102301-05-3
• 化学式: C₁₅H₁₇N₅O₄S
• 分子量: 363.397
• InChiKey: FLIAIAPHMPCKCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  148
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND
  申请人：Lokhov Sergey

  公开号：US20080293586A1

  公开（公告）日：2008-11-27

  Minor groove binder-oligonucleotide probes are provided along with methods for their use wherein the probes have an attached fluorophore which, in an unhybridized form exhibits very low background signal.

  提供了微小沟结合剂寡核苷酸探针以及其使用方法，其中探针具有附加的荧光物质，未杂交形式的荧光物质信号非常低。
• FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS
  申请人：Reed Michael W.

  公开号：US20100174058A1

  公开（公告）日：2010-07-08

  Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group.

  提供了含有两个标签的寡核苷酸探针，适用于杂交检测。这些探针还可以包含一个次级沟结合基团。
• Thermal transfer printing
  申请人：ZENECA LIMITED

  公开号：EP0216483A1

  公开（公告）日：1987-04-01

  A thermaltransfer printing sheet comprising a substrate having a coating comprising at least one azo dye of the formula: wherein A is the residue of a diazotisable heteroaromatic amine, A-NH7, in which A is selected from imidazolyl, pyrazolyl, thiazolyl, benzothiazolyl, isothiazolyl, benzoisothiazolyl, pyridoisothiazolyl & thienyl & E is the residue of an aromatic coupling component, E-X wherein X is a group displaceable by a diazotised aromatic amine and E is optionally substituted aminophenyl, tetrahydroquinolinyl, julolidyl or aminoquinolmyl. and a process for the transfer of dye from the transfer sheet to a receiver sheet by the selective application of heat to the transfer sheet while it is contact with the receiver sheet.

  一种热转印印花片材，包括具有至少一种式偶氮染料涂层的基材： 其中 A是可重氮化的杂芳香族胺A-NH7的残基，其中A选自咪唑基、吡唑基、噻唑基、苯并噻唑基、异噻唑基、苯并异噻唑基、吡啶异噻唑基和噻吩基 & E 是芳香偶联组分的残基，E-X 其中 X 是可被重氮化芳香胺置换的基团，E 是任选取代的氨基苯基、四氢喹啉基、久洛烷基或氨基喹啉基。 以及一种在转印片与接收片接触时选择性地对其加热，从而将染料从转印片转移到接收片的工艺。
• Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis
  申请人：Afonina A. Irina

  公开号：US20070003957A1

  公开（公告）日：2007-01-04

  Oligonucleotide probes/conjugates are provided along with method for their use in assays to monitor amplification wherein the signal produced does not rely on 5′ nuclease digestion.
• AMPLIFICATION METHODS
  申请人：MAHONEY WALT

  公开号：US20080248474A1

  公开（公告）日：2008-10-09

  Methods are provided for amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe.