1-[1-(Dimethylsulfamoylamino)but-3-enyl]-3-nitrobenzene | 1153630-37-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[1-(Dimethylsulfamoylamino)but-3-enyl]-3-nitrobenzene
• CAS: 1153630-37-5
• 化学式: C₁₂H₁₇N₃O₄S
• 分子量: 299.351
• InChiKey: WMPFZLNYPXCCNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  104
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  烯丙基三丁基锡 、 N-(dimethylsulfamoyl)-m-nitrobenzaldimine 在 resorcinolbis[(diphenyl)phosphinite] palladium trifluoroacetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 16.0h， 以93%的产率得到1-[1-(Dimethylsulfamoylamino)but-3-enyl]-3-nitrobenzene
  参考文献：
  名称：

  P′CP′-Pincer palladium complex-catalyzed allylation of N,N-dimethylsulfamoyl-protected aldimines

  摘要：

  The P'CP'-pincer palladium complex-catalyzed allylation of N,N-dimethylsulfamoyl-protected aldimines with allyl(tributyl)stannane is investigated for the preparation of N-homoallylic sulfamides. The desired N,N-dimethylsulfamoyl-protected products are obtained in moderate to high yields in DMF under very mild conditions and a high yielding and convenient deprotection of the N,N-dimethylsulfamoyl group is also demonstrated. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.187

文献信息

• P′CP′-Pincer palladium complex-catalyzed allylation of N,N-dimethylsulfamoyl-protected aldimines
  作者：Jie Li、Adriaan J. Minnaard、Robertus J.M. Klein Gebbink、Gerard van Koten

  DOI：10.1016/j.tetlet.2009.02.187

  日期：2009.5

  The P'CP'-pincer palladium complex-catalyzed allylation of N,N-dimethylsulfamoyl-protected aldimines with allyl(tributyl)stannane is investigated for the preparation of N-homoallylic sulfamides. The desired N,N-dimethylsulfamoyl-protected products are obtained in moderate to high yields in DMF under very mild conditions and a high yielding and convenient deprotection of the N,N-dimethylsulfamoyl group is also demonstrated. (C) 2009 Elsevier Ltd. All rights reserved.