5,6,5',6'-tetrafluoro-1H,1'H-[2,2']bibenzoimidazolyl | 1189399-42-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 5,6,5',6'-tetrafluoro-1H,1'H-[2,2']bibenzoimidazolyl
• 英文别名: 2-(5,6-difluoro-1H-benzimidazol-2-yl)-5,6-difluoro-1H-benzimidazole
• CAS: 1189399-42-5
• 化学式: C₁₄H₆F₄N₄
• 分子量: 306.222
• InChiKey: IFAJDHBGAFXWSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  57.4
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION
  申请人：Dai Dongcheng

  公开号：US20110027227A1

  公开（公告）日：2011-02-03

  Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family is disclosed.
• Antiviral Drugs for Treatment of Arenvirus Infection
  申请人：SIGA TECHNOLOGIES, INC.

  公开号：US20140100245A1

  公开（公告）日：2014-04-10

  Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family is disclosed.
• US8623347B2
  申请人：——

  公开号：US8623347B2

  公开（公告）日：2014-01-07
• [EN] ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION<br/>[FR] MÉDICAMENTS ANTIVIRAUX POUR LE TRAITEMENT D'UNE INFECTION PAR UN ARÉNAVIRUS
  申请人：SIGA TECHNOLOGIES INC

  公开号：WO2009123776A2

  公开（公告）日：2009-10-08

  Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family is disclosed.