tert-butylphosphirane | 188658-03-9

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: tert-butylphosphirane
• 英文别名: 1-Tert-butylphosphirane
• CAS: 188658-03-9
• 化学式: C₆H₁₃P
• 分子量: 116.143
• InChiKey: UNDXXNIVELTZQT-UHFFFAOYSA-N

物化性质

• 沸点：
  123.7±7.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  六羰基钨 、 tert-butylphosphirane 在 THF 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 以90%的产率得到(tert-butylphosphirane)pentacarbonyltungsten
  参考文献：
  名称：

  Synthesis and Reactivity of Phosphirane Ligands and the Structural Characterization of Cp*IrCl₂(tert-butylphosphirane)

  摘要：

  New and stable phosphiranes, tert-butylphosphirane and xylylphosphirane, were prepared. tert-Butylphosphirane is stable to polymerization in the presence of electrophiles. It was reacted with bis((mu-chloro)chloro(pentamethylcyclopentadienyl)iridium) to prepare (tert-butylphosphirane)dichloro(pentamethylcyclopentadienyl)iridium, which was characterized by X-ray diffraction, tert-Butylphosphirane was also reacted with pentacarbonyl(tetrahydrofuran)tungsten and borane to form (tert-butylphosphirane)pentacarbonyltungsten and the first phosphirane-borane adduct, respectively.

  DOI：

  10.1021/om960400o

文献信息

• FACTOR IX POLYPEPTIDES AND METHODS OF USE THEREOF
  申请人：BIOVERATIV THERAPEUTICS INC.

  公开号：US20210023185A1

  公开（公告）日：2021-01-28

  The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.