ap-2-methyl-2-(1,2,3,4-tetrachloro-9-triptycyl)propyl acetate | 127393-73-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: ap-2-methyl-2-(1,2,3,4-tetrachloro-9-triptycyl)propyl acetate
• 英文别名: sc-2-methyl-2-(1,2,3,4-tetrachloro-9-triptycyl)propyl acetate；2-methyl-2-(1,2,3,4-tetrachloro-9-triptycyl)propyl acetate；[2-Methyl-2-(3,4,5,6-tetrachloro-1-pentacyclo[6.6.6.02,7.09,14.015,20]icosa-2(7),3,5,9,11,13,15,17,19-nonaenyl)propyl] acetate
• CAS: 127393-73-1
• 化学式: C₂₆H₂₀Cl₄O₂
• 分子量: 506.256
• InChiKey: PSNFDWXRJYHJSV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-Methyl-3-(3,4,5,6-tetrachloro-1-pentacyclo[6.6.6.02,7.09,14.015,20]icosa-2(7),3,5,9,11,13,15,17,19-nonaenyl)butanoic acid 在 盐酸 、 氢氧化钾 、 sodium azide 、 溶剂黄146 、 叔丁醇 、 亚硝酸异戊酯 作用下， 以 苯 为溶剂， 生成 ap-2-methyl-2-(1,2,3,4-tetrachloro-9-triptycyl)propyl acetate
  参考文献：
  名称：

  Tanaka, Yasuhiro; Yamamoto, Gaku; Oki, Michinori, Chemistry Letters, 1989, p. 2019 - 2022

  摘要：

  DOI：

文献信息

• Syntheses of Rotational Isomers of Substituted 9-<i>t</i>-Butyltriptycenes That Carry an Oxygen Substituent in<i>t</i>-Butyl Group and Outstanding Steric Effects Observed in the Synthesis of an Intermediate
  作者：Michinori Oki、Tsutomu Miyasaka、Osamu Katafuchi、Takayuki Ishizuka、Shinji Toyota

  DOI：10.1246/bcsj.67.3076

  日期：1994.11

  The title rotational isomers were synthesized. Reduction of methyl 2-(9-anthryl)-2-methylpropanoate caused difficulty due to severe steric effects. Thus the compound was converted to the free acid by treating it with a lithium thiolate and the resulted acid was reduced to the corresponding alcohol with borane. The alcohol was protected as either an acetate or a silyl ether and was subjected to the

  合成了标题旋转异构体。由于严重的空间效应，2-(9-蒽基)-2-甲基丙酸甲酯的还原造成困难。因此，该化合物通过用硫醇锂处理而转化为游离酸，所得酸用硼烷还原为相应的醇。醇被保护为乙酸酯或甲硅烷基醚，并与苄进行反应。所得三苯乙烯的旋转异构体通过色谱法分离。制备了带有乙酰氧基、羟基或叔丁氧基取代基的旋转异构体。
• Reactivities of Stable Rotamers. XLIII. Diazotization of 2-Methyl-2-(1,2,3,4-tetrachloro- and 1,4-dimethoxy-9-triptycyl)propylamine Rotamers
  作者：Michinori Oki、Satoshi Yoshida、Yasushi Taguchi、Ichiro Minato、Koji Nobuoka、Norihiro Fukada、Shinji Toyota、Toshimasa Tanaka、Yasuhiro Tanaka、Gaku Yamamoto

  DOI：10.1246/bcsj.73.2563

  日期：2000.11

  derived by the attack of the carbocation on an unsubstituted benzeno bridge and esters derived from the acid which was used for diazotization. These two compounds are the products from the cation prior to the rearrangement. The sc-tetrachloro compound afforded the esters of the organic acids as almost an exclusive product and the sc-dimethoxy compound afforded a cyclized compound which is derived from

  标题胺是由相应的羧酸旋转异构体通过叠氮化物和异氰酸酯制备的。这些胺与亚硝酸异戊酯和有机酸的重氮化通常得到烯烃，这些烯烃源自介入阳离子的 Wagner-Meerwein 型重排，然后去质子化。其他产品包括通过碳正离子攻击未取代的苯桥而衍生的环状化合物和衍生自用于重氮化的酸的酯。这两种化合物是重排前阳离子的产物。sc-四氯化合物提供有机酸的酯作为几乎唯一的产物，sc-二甲氧基化合物提供环化化合物，其衍生自 1-甲氧基与阳离子的亲核反应，然后对所得氧鎓离子进行去甲基化。这些特征归因于 1-取代基与中间碳正离子的强相互作用。同意...
• TANAKA, YASUHIRO;YAMAMOTO, GAKU;OKI, MICHINORI, CHEM. LETT.,(1989) N1, C. 2019-2022
  作者：TANAKA, YASUHIRO、YAMAMOTO, GAKU、OKI, MICHINORI

  DOI：——

  日期：——