12,25,38-trisdiazo-1,4,7,10,14,17,20,23,27,30,33,36-dodecaoxacyclononatriacontane-11,13,24,26,37,39-hexaone | 1006060-45-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 12,25,38-trisdiazo-1,4,7,10,14,17,20,23,27,30,33,36-dodecaoxacyclononatriacontane-11,13,24,26,37,39-hexaone
• CAS: 1006060-45-2
• 化学式: C₂₇H₃₆N₆O₁₈
• 分子量: 732.612
• InChiKey: CMEWDHOTAMZZFM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.63
• 重原子数：
  51.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  322.38
• 氢给体数：
  0.0
• 氢受体数：
  18.0

反应信息

• 作为产物：
  描述：

  1,4,7,10,14,17,20,23,27,30,33,36-dodecaoxacyclononatriacontane-11,13,24,26,37,39-hexaone 在 4-乙酰氨基苯磺酰叠氮 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 二氯甲烷 为溶剂， 以40%的产率得到12,25,38-trisdiazo-1,4,7,10,14,17,20,23,27,30,33,36-dodecaoxacyclononatriacontane-11,13,24,26,37,39-hexaone
  参考文献：
  名称：

  Reactions of macrocyclic rhodium carbenoids: regioselective synthesis of indol-3-yl macrocyclic lactones and cryptands

  摘要：

  A wide variety of new macrocyclic diazocarbonyl compounds with various spacers was synthesized. Macrocyclic rhodium(H) carberioid insertion with various substituted indoles was performed to afford regioselectively, indol-3-yl macrocyclic di- or tetralactones (C3-alkylation). Double carberioid insertion was also performed to afford indolyl cryptand molecules. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.102