2,5-dicyclohexyl-1-phenylphosphole | 448901-38-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,5-dicyclohexyl-1-phenylphosphole
• 英文别名: 1-phenyl-2,5-dicyclohexylphosphole
• CAS: 448901-38-0
• 化学式: C₂₂H₂₉P
• 分子量: 324.446
• InChiKey: WPSKRKJVUXBPKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2,5-dicyclohexyl-1-phenylphosphole 在 lithium 、 aluminum (III) chloride 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  锇的制备η 5个-Phospholide配合物及其与酰基电体的反应：C = O键的断裂和C-C键形成的金属配位层内

  摘要：

  两个diphosphaosmocene物种由锂2,5- dialkylphospholide的反应被预缩减以优良产率（烷基=环己基，（ - ） -薄荷基）和[（η 6 -cymene）OSCL 2 ] 2的THF溶液。这些是具有core核的磷酸金属茂的第一个实例。对于成功的磷茂茂合成，至关重要的是使用空间需求的磷化物。用二氯甲烷中的AcCl / AlCl 3混合物处理2,2'，5,5'-Cy 4-二磷茂茂，通过乙酰基C═O双键的活化产生新型（μ-亚乙烯基）os配合物。在锇络合物，锇原子和η的磷之间的μ -偏二部分桥4 - （P-氧代磷化物）。在过量的乙酰基亲电试剂的存在下，使μ-亚乙烯基络合物在μ-亚乙烯基部分的CH 2末端进一步乙酰化，得到（μ-乙酰基亚乙烯基）os络合物。在此转化过程中逐步应用乙酰氯和苯乙酰氯，可以通过在两个不同的酰氯之间形成C-C键来生产[μ-（苯乙酰基）亚乙烯基] os。

  DOI：

  10.1021/om101060n

文献信息

• Synthesis and Characterization of 1,1‘-Diphospharuthenocenes
  作者：Masamichi Ogasawara、Takashi Nagano、Kazuhiro Yoshida、Tamio Hayashi

  DOI：10.1021/om020189i

  日期：2002.7.1

  Reaction of [RuCl2(cod)](n) (cod = 1,5-cyclooctadiene) with lithium 2,5-dialkylphospholide or 1-stannyl-2,5-dialkylphosphole gives Ru(eta(5)-PC4H2-2,5-R-2)(2) (R = (-)-menthyl, 4a; or cyclohexyl, 4b). Steric bulkiness of the R groups is a crucial factor for the successful preparation of the 1,1'-diphospharuthenocenes. The structure of the complex 4b was studied by X-ray single-crystal structure determination, which clarified the distance between the nearly planar eta(5)-phospholyl ligand and the ruthenium center in the complex, being 1.811 Angstrom.
• Coordination behavior of phosphino-phosphaferrocenes: monodentate versus bidentate coordination to divalent palladium
  作者：Masamichi Ogasawara、Yonghui Ge、Kiyohiko Nakajima、Tamotsu Takahashi

  DOI：10.1016/j.ica.2004.05.019

  日期：2004.11

  Two novel phosphino-phosphaferrocenes [eta(5)-C5H4(CH2)(n)PPh2]Fe(eta(5)-PC4H2-2,5-cy(2)) (PP1: n = 1; PP2: n = 2) have been designed and prepared in order to clarify weak chelate effect in the previously reported (eta(5)-C5H4CH2PPh2)Fe[eta(5)-PC4H2-2,5-((-)-menthyl)(2)] (1). P-31 NMR studies of reactions of PP1 with PdCl2(cod) (6) revealed that PP1 showed stronger tendency to coordinate to the Pd-II center in bidentate fashion compared to 1. On the other hand, chelate effect in PP2 was negligibly weak and a reaction of PP2 with 6 in a PP2/6 = 2/1 molar ratio gave a complex PdCl2(PP2)(2) (10) cleanly in which PP2 coordinated to the palladium center at the PPh2 moiety as a monodentate ligand. X-ray crystal structure studies of chelate complexes PdCl(2()PP1) (7) and PdCl2(PP2) (9) showed that 9 had deviations from an idealized geometry in the square planar complex which could be attributed to a larger chelate ring of PP2, while PP1 in 7 constructed nearly ideal geometry for the square planar complex.From comparison of the coordination behavior between 1, PP1, and PP2, it is concluded that steric bulk of (-)-menthyl groups in I is the main factor of the weak chelate coordination of 1. (C) 2004 Elsevier B.V. All rights reserved.