cibotiglycerol | 1187547-10-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: cibotiglycerol
• 英文别名: (2S)-1-O-(9Z,12Z-octadecadienoyl)-3-O-(6-sulfo-α-D-quinovopyranosyl)glycerol sodium salt；sodium;[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-hydroxy-3-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropoxy]oxan-2-yl]methanesulfonate
• CAS: 1187547-10-9
• 化学式: C₂₇H₄₇O₁₁S*Na
• 分子量: 602.719
• InChiKey: SWAAQLHEPIHCND-YYZFRIICSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.92
• 重原子数：
  40
• 可旋转键数：
  22
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  191
• 氢给体数：
  4
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  cibotiglycerol 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 0.17h， 生成 3-α-D-sulfoquinovosyl-sn-glycerol
  参考文献：
  名称：

  Inhibitors of Osteoclast Formation from Rhizomes of Cibotium barometz

  摘要：

  Eight compounds (1-8) were isolated from a methanol extract of Cibotium barometz rhizomes including two new furan derivatives, cibotiumbarosides A (1) and B (2), and a new glycoglycerolipid, cibotiglycerol (4). Their structures were elucidated by chemical and spectroscopic methods. Compounds 2-5 each showed inhibition of osteoclast formation with no affect on BMM cell viability.

  DOI：

  10.1021/np9004097

文献信息

• Inhibitors of Osteoclast Formation from Rhizomes of <i>Cibotium barometz</i>
  作者：Nguyen Xuan Cuong、Chau Van Minh、Phan Van Kiem、Hoang Thanh Huong、Ninh Khac Ban、Nguyen Xuan Nhiem、Nguyen Huu Tung、Ji-Won Jung、Hyun-Ju Kim、Shin-Yoon Kim、Jeong Ah Kim、Young Ho Kim

  DOI：10.1021/np9004097

  日期：2009.9.25

  Eight compounds (1-8) were isolated from a methanol extract of Cibotium barometz rhizomes including two new furan derivatives, cibotiumbarosides A (1) and B (2), and a new glycoglycerolipid, cibotiglycerol (4). Their structures were elucidated by chemical and spectroscopic methods. Compounds 2-5 each showed inhibition of osteoclast formation with no affect on BMM cell viability.