2-chloro-4-(3',3'-dichloroallyloxy)phenol | 378187-53-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-chloro-4-(3',3'-dichloroallyloxy)phenol
• 英文别名: 2-Chloro-4-(3,3-dichloroprop-2-enoxy)phenol
• CAS: 378187-53-2
• 化学式: C₉H₇Cl₃O₂
• 分子量: 253.512
• InChiKey: BZPNQSUSIIOGKR-UHFFFAOYSA-N

物化性质

• 沸点：
  383.6±42.0 °C(Predicted)
• 密度：
  1.465±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-chloro-4-(3',3'-dichloroallyloxy)phenol 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 、 乙腈 为溶剂， 反应 2.0h， 生成 3-chloro-2-(4-(3-(2-chloro-4-((3,3-dichloroallyl)oxy)phenoxy)propoxy)phenoxy)-5-(trifluoromethyl)pyridine
  参考文献：
  名称：

  Design, synthesis and insecticidal evaluation of aryloxy dihalopropene derivatives

  摘要：

  Plutella xylostella (P. xylostella) is a highly migratory, cosmopolitan species and one of the most important pest of cruciferous crops worldwide. Pyridalyl as a novel class of insecticides has good efficacy against P. xylostella. On the basis of the commercial insecticide pyridalyl, a series of new aryloxy dihalopropene derivatives were designed and synthesized by using Intermediate Derivatization Methods. Their chemical structures were confirmed by H-1 NMR, high-resolution mass spectrum (HRMS), and single-crystal X-ray diffraction analysis. The insecticidal activities of the new compounds against P. xylostella were evaluated. The results of bioassays indicated that most of the compounds showed moderate to high activities at the tested concentration, especially compounds 10e and 10g displayed more than 75% insecticidal activity against P. xylostella at 6.25 mg/L, while pyridalyl showed 50% insecticidal activity at the same concentration. The field trials result of the insecticidal activities showed that compound 10e as a 10% emulsifiable concentrate (EC) was effective in the control of P. xylostella at 75-150 g a. i./ha, and the mortality of P. xylostella for treatment with compound 10e at 75 g a. i./ha was equivalent to pyridalyl at 105 g a.i./ha. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2015.09.030
• 作为产物：
  描述：

  4-(3,3-dichloroallyloxy)phenol 在 氯化亚砜 、 二正丁胺 作用下， 以 甲苯 为溶剂， 反应 1.0h， 以85%的产率得到2-chloro-4-(3',3'-dichloroallyloxy)phenol
  参考文献：
  名称：

  Ether Compounds with Nitrogen-Containing 5-Member Heterocycle and Uses Thereof

  摘要：

  本发明涉及具有含氮的5元杂环的醚化合物，代表式为(I)：其中所述基团如规范中定义。本发明的化合物具有广谱杀虫活性，对包括欧洲玉米螟、甘蔗螟、夏季水果蛾、Grapholitha inopinata、Lymantria dispar、Cnaphalocrocis medialis、Pyrausta nubilalis、Heliothis assulta、Grapholitha molesta、Plutella xylostella、Laphygma exigua、Prodenialitura等鳞翅目害虫特别是对Plutella xylostella和Laphygma exigua更为有效，在非常低的剂量下也可以产生非常好的效果。本发明的化合物对蚜虫等同翅目害虫也具有高活性。同时，本发明的一些化合物具有非常好的杀真菌活性，可用于防治小麦白粉病、黄瓜霜霉病、蔬菜灰霉病等。

  公开号：

  US20110178149A1

文献信息

• PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2039671B1

  公开（公告）日：2011-08-31
• US7652177B2
  申请人：——

  公开号：US7652177B2

  公开（公告）日：2010-01-26