10,20-dihydroxy DPAn-3 | 887752-34-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 10,20-dihydroxy DPAn-3
• 英文别名: (7Z,11Z,13Z,16Z,18E)-10,20-dihydroxydocosa-7,11,13,16,18-pentaenoic acid
• CAS: 887752-34-3
• 化学式: C₂₂H₃₄O₄
• 分子量: 362.51
• InChiKey: KMHQHGCEUDYSGN-DYWDTJGBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  26
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE
  申请人：Gjorstrup Per

  公开号：US20110190242A1

  公开（公告）日：2011-08-04

  The invention relates to methods of treating inflammatory disease comprising administering a compound of formula A, a compound of any one of formulae 1-49 or I-III, a lipoxin compound, or an oxylipin compound.

  该发明涉及治疗炎症性疾病的方法，包括给予公式A的化合物、任何一个公式1-49或I-III的化合物、脂氧素化合物或氧脂素化合物。
• COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION
  申请人：C.T. Resolve SARL

  公开号：EP2419399B1

  公开（公告）日：2016-03-23
• Compositions and methods for the treatment of cardiovascular disease
  申请人：Gjorstrup Per

  公开号：US20070254897A1

  公开（公告）日：2007-11-01

  The invention relates to methods of treating cardiovascular disease comprising administering a resolvin, lipoxin, or oxylipin compound.
• Compositions and methods for the treatment of inflammatory disease
  申请人：Gjorstrup Per

  公开号：US20080161275A1

  公开（公告）日：2008-07-03

  The invention relates to methods of treating inflammatory disease comprising administering a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound.
• Compounds and methods for inhibition of bone loss
  申请人：Gjorstrup Per

  公开号：US20080161274A1

  公开（公告）日：2008-07-03

  The invention relates to methods of treating or preventing bone loss, as in osteoporosis, metastatic bone disease, or periodontitis, comprising administering a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound.