methyl (8E,10E,12R)-12-hydroxypentadeca-8,10-dien-6,14-diynoate | 1220354-10-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl (8E,10E,12R)-12-hydroxypentadeca-8,10-dien-6,14-diynoate
• CAS: 1220354-10-8
• 化学式: C₁₆H₂₀O₃
• 分子量: 260.333
• InChiKey: DZPAJQZVAZOKMU-RNTLHFRESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE
  申请人：Gjorstrup Per

  公开号：US20110190242A1

  公开（公告）日：2011-08-04

  The invention relates to methods of treating inflammatory disease comprising administering a compound of formula A, a compound of any one of formulae 1-49 or I-III, a lipoxin compound, or an oxylipin compound.

  该发明涉及治疗炎症性疾病的方法，包括给予公式A的化合物、任何一个公式1-49或I-III的化合物、脂氧素化合物或氧脂素化合物。
• COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION
  申请人：C.T. Resolve SARL

  公开号：EP2419399B1

  公开（公告）日：2016-03-23
• THERAPEUTIC COMPOUNDS
  申请人：Schwartz C. Eric

  公开号：US20110245528A1

  公开（公告）日：2011-10-06

  The invention relates to novel resolvin compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel resolvin compounds of the invention.
• COMPOSITIONS AND METHODS FOR ORGAN PRESERVATION
  申请人：Gjorstrup Per

  公开号：US20120122816A1

  公开（公告）日：2012-05-17

  The invention relates to reducing, preventing or reversing organ damage, reducing and/or preventing stem cell damage and/or death, enhancing organ preservation and/or survival, or enhancing stem cell preservation and/or survival comprising administering a compound of formula A, a compound of any one of formulae 1-49 or I-III, a lipoxin compound, an oxylipin compound, or a combination of aspirin and an omega-3 fatty acid.
• US20140275247A1
  申请人：——

  公开号：US20140275247A1

  公开（公告）日：2014-09-18