linoleoyl-L-isoleucinol | 1186629-21-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: linoleoyl-L-isoleucinol
• 英文别名: (9Z,12Z)-N-[(2S,3S)-1-hydroxy-3-methylpentan-2-yl]octadeca-9,12-dienamide
• CAS: 1186629-21-9
• 化学式: C₂₄H₄₅NO₂
• 分子量: 379.627
• InChiKey: UGNRYCIRCBMPER-LBDVSKOWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  27
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• COMPOUNDS AND METHODS OF TREATING OBESITY
  申请人：Katzhendler Jehoshua

  公开号：US20110178151A1

  公开（公告）日：2011-07-21

  The present invention relates to novel fatty acid derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as agents for the treatment of obesity and related disorders, and for improving cognition.

  本发明涉及一种新型脂肪酸衍生物、其制备方法、包括这些化合物的制药组合物，以及使用这些化合物和组合物的方法，特别是作为治疗肥胖和相关疾病的药物和改善认知能力的药物。
• US9428448B2
  申请人：——

  公开号：US9428448B2

  公开（公告）日：2016-08-30
• [EN] COMPOUNDS AND METHODS OF TREATING OBESITY<br/>[FR] COMPOSÉS ET PROCÉDÉS POUR LE TRAITEMENT DE L'OBÉSITÉ
  申请人：YISSUM RES DEV CO

  公开号：WO2009109973A2

  公开（公告）日：2009-09-11

  The present invention relates to novel fatty acid derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as agents for the treatment of obesity and related disorders, and for improving cognition.