3-甲基-N-(1-甲基乙基)-2-硝基苯甲酰胺 | 362640-53-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3-甲基-N-(1-甲基乙基)-2-硝基苯甲酰胺
• 英文名称: 3-methyl-N-(1-methylethyl)-2-nitrobenzamide
• 英文别名: 3-methyl-2-nitro-N-propan-2-ylbenzamide
• CAS: 362640-53-7
• 化学式: C₁₁H₁₄N₂O₃
• mdl: MFCD03639341
• 分子量: 222.244
• InChiKey: ZNZJTSGMNMHUOB-UHFFFAOYSA-N

物化性质

• 沸点：
  340.5±35.0 °C(Predicted)
• 密度：
  1.161±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  74.9
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-甲基-N-(1-甲基乙基)-2-硝基苯甲酰胺 在 palladium on activated charcoal 氢气 、 N,N-二异丙基乙胺 作用下， 以 乙醇 、 氯仿 为溶剂， 生成 2-ethyl-N-[2-methyl-6-(propan-2-ylcarbamoyl)phenyl]-6-(trifluoromethyl)pyridine-3-carboxamide
  参考文献：
  名称：

  Insecticidal anthranilic diamides: A new class of potent ryanodine receptor activators

  摘要：

  A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.08.034
• 作为产物：
  描述：

  3-甲基-2-硝基苯甲酸 、 异丙胺 在 氯甲酸乙酯 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 以1.96 g的产率得到3-甲基-N-(1-甲基乙基)-2-硝基苯甲酰胺
  参考文献：
  名称：

  Anthranilamide arthropodicide treatment

  摘要：

  这项发明涉及一种保护繁殖体或从中生长的植物免受无脊椎动物害虫侵害的方法，包括将繁殖体或繁殖体的位置与化合物I的生物有效量，其N-氧化物或农业适用盐之一接触，其中A和B以及R1至R8如披露中所定义。该发明还涉及用化合物I处理过的繁殖体和包含化合物I的配方用于包覆繁殖体。

  公开号：

  US09173400B2

文献信息

• Insecticidal anthranilamides
  申请人：——

  公开号：US20030229050A1

  公开（公告）日：2003-12-11

  This invention provides compounds of Formula (1), their N-oxides and agriculturally suitable salts wherein A, B, J, R 1 , R 2 , R 3 and R 4 and n are as defined in the disclosure. Also disclosed are methods for controlling arthropods comprising contacting the arthropods or their environment with an arthropodicidally effective amount of a compound of Formula (1) and compositions containing the compounds of Formula (1).

  这项发明提供了公式（1）的化合物，它们的N-氧化物和农业适用的盐，其中A、B、J、R1、R2、R3和R4以及n如披露中定义。还披露了控制节肢动物的方法，包括将节肢动物或其环境与公式（1）的化合物的有效量接触，并含有公式（1）的化合物的组合物。
• Method of controlling particular insect pests by applying anthranilamide compounds
  申请人：E I DU PONT DE NEMOURS AND COMPANY

  公开号：US09113630B2

  公开（公告）日：2015-08-25

  This invention pertains to a method for controlling lepidopteran, homopteran, hemipteran, thysanopteran and coleopteran insect pests comprising contacting the insects or their environment with an arthropodicidally effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R1 through R8 are as defined in the disclosure. This invention further relates to a benzoxazinone compound of Formula 10 wherein R4 through R8 are as defined in the disclosure, useful for preparation of a compound of Formula I.

  这项发明涉及一种控制鳞翅目、同翅目、半翅目、鳞翅目和鞘翅目昆虫害虫的方法，包括将昆虫或其环境与化合物I的有效量，其N-氧化物或农业适用的盐接触，其中A和B以及R1至R8如披露中定义。该发明还涉及化合物10的苯并噁唑酮化合物，其中R4至R8如披露中定义，用于制备化合物I。
• Anthranilamide arthropodicide treatment
  申请人：E I DU PONT DE NEMOURS AND COMPANY

  公开号：US09173400B2

  公开（公告）日：2015-11-03

  This invention pertains to methods for protecting a propagule or a plant grown therefrom from invertebrate pests comprising contacting the propagule or the locus of the propagule with a biologically effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R1 through R8 are as defined in the disclosure. This invention also relates to propagules treated with a compound of Formula I and compositions comprising a Formula I compound for coating propagules.

  这项发明涉及一种保护繁殖体或从中生长的植物免受无脊椎动物害虫侵害的方法，包括将繁殖体或繁殖体的位置与化合物I的生物有效量，其N-氧化物或农业适用盐之一接触，其中A和B以及R1至R8如披露中所定义。该发明还涉及用化合物I处理过的繁殖体和包含化合物I的配方用于包覆繁殖体。
• Quinazolinones and pyridinylpyrimidinones for controlling invertebrate pests
  申请人：——

  公开号：US20040110777A1

  公开（公告）日：2004-06-10

  This invention provides methods for controlling invertebrate pests comprising contacting the pests or their environment with an arthropodicidally effective amount of a compound of Formula (I), its N-oxides or agriculturally suitable salts wherein B, J, K, R 3 and R 4 and n are as defined in the disclosure.This invention also pertains to certain compounds of Formula (I) and compositions for controlling invertebrate pests comprising a biologically effective amount of a compound of Formula I and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid diluents. 1

  这项发明提供了控制无脊椎动物害虫的方法，包括使用化合物I的有效量与害虫或其环境接触，其中化合物I的化学式为（I），其N-氧化物或农业适用盐，其中B、J、K、R3和R4和n如披露中所定义。该发明还涉及化合物I的某些化合物和用于控制无脊椎动物害虫的组合物，包括化合物I的生物学有效量和至少一种选自表面活性剂、固体稀释剂和液体稀释剂的附加成分。
• Method for controlling particular insect pest by applying anthranilamide compounds
  申请人：Lahm Philip George

  公开号：US20050075372A1

  公开（公告）日：2005-04-07

  This invention pertains to a method for controlling lepidopteran, homopteran, hemipteran, thysanopteran and coleopteran insect pests comprising contacting the insects or their environment with an arthropodicidally effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R 1 through R 8 are as defined in the disclosure. This invention further relates to a bezoxazinone compound of Formula 10 wherein R 4 through R 8 are as defined in the disclosure, useful for preparation of a compound of Formula I.

  本发明涉及一种控制鳞翅目、同翅目、半翅目、蓟马目和鞘翅目昆虫害的方法，包括将昆虫或其环境与公式I的化合物、其N-氧化物或其农业适用盐的节肢动物杀虫剂有效量接触，其中A和B和R1到R8如本公开说明书所定义。本发明还涉及一种公式10的苯并噁嗪化合物，其中R4到R8如本公开说明书所定义，用于制备公式I的化合物。