α-Hydroxy-pimelinsaeure-diethylester | 100048-70-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: α-Hydroxy-pimelinsaeure-diethylester
• 英文别名: Diethyl 2-hydroxyheptanedioate
• CAS: 100048-70-2
• 化学式: C₁₁H₂₀O₅
• 分子量: 232.277
• InChiKey: TWSBBOUNFHSFRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  16
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• PREPARATION OF ALPHA-KETOPIMELIC ACID
  申请人：Raemakers-Franken Petronella Catharina

  公开号：US20120231512A1

  公开（公告）日：2012-09-13

  The present invention relates to a method for preparing alpha-ketopimelic acid, comprising converting 2-hydroxyheptanedioic acid into alpha-ketopimelic acid, which conversion is catalysed using a biocatalyst. Further, the invention relates to a heterologous cell, comprising a nucleic acid sequence encoding an enzyme having catalytic activity in the conversion of 2-hydroxyheptanedioic acid into alpha-ketopimelic acid. Further, the invention relates to the use of a heterologous cell according to the invention in the preparation of caprolactam, diaminohexane or adipic acid.
• [EN] PREPARATION OF ALPHA-KETOPIMELIC ACID<br/>[FR] PRÉPARATION DE L'ACIDE ALPHA-CÉTOPIMÉLIQUE
  申请人：DSM IP ASSETS BV

  公开号：WO2011031146A2

  公开（公告）日：2011-03-17

  The present invention relates to a method for preparing alpha-ketopimelic acid, comprising converting 2-hydroxyheptanedioic acid into alpha-ketopimelic acid, which conversion is catalysed using a biocatalyst. Further, the invention relates to a heterologous cell, comprising a nucleic acid sequence encoding an enzyme having catalytic activity in the conversion of 2-hydroxyheptanedioic acid into alpha-ketopimelic acid. Further, the invention relates to the use of a heterologous cell according to the invention in the preparation of caprolactam, diaminohexane or adipic acid.