N-methyltridecanamide | 6225-11-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-methyltridecanamide
• 英文别名: Tridecansaeure-methylamid；N-Methyl-tridecanamid
• CAS: 6225-11-2
• 化学式: C₁₄H₂₉NO
• 分子量: 227.39
• InChiKey: PKDVDHHRICWWGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] PROCESS FOR PRODUCING NITROGEN-CONTAINING COMPOUNDS<br/>[FR] PROCÉDÉ DE PRODUCTION DE COMPOSÉS AZOTÉS
  申请人：KAO CORP

  公开号：WO2009020244A1

  公开（公告）日：2009-02-12

  The present invention relates to a process for producing a tertiary amine in the presence of a catalyst containing copper and at least one element selected from the group consisting of elements belonging to Groups 2, 3, 7 and 12 of the Periodic Table (long form of the periodic table), said process including the steps of (a) reducing an amide compound in a hydrogen atmosphere; and (b) introducing a dialkyl amine containing a linear or branched alkyl group having 1 to 6 carbon atoms into a reaction product obtained in the step (a), and treating the reaction product with the dialkyl amine. The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products by reducing aliphatic acid amides under moderate conditions using a chromium-free catalyst, as well as a process for producing amine derivatives such as amine oxide by using the aliphatic tertiary amines, with a good productivity in an economical manner.

  本发明涉及一种在含有铜和周期表长形式中属于2、3、7和12族元素之一的至少一种元素的催化剂存在下生产三级胺的方法，该方法包括以下步骤：(a) 在氢气氛中还原酰胺化合物；和(b) 将含有1至6个碳原子的线性或支链烷基基团的二烷基胺引入在步骤(a)中获得的反应产物中，并用二烷基胺处理反应产物。本发明提供了一种在中等条件下使用无铬催化剂还原脂肪酸酰胺从而生产含有较少副产物的高纯度脂肪族三级胺的方法，以及一种通过使用脂肪族三级胺生产胺氧化物等胺衍生物的方法，具有良好的经济生产能力。
• NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS
  申请人：DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL

  公开号：US20150111935A1

  公开（公告）日：2015-04-23

  The present invention relates to a novel class of 1,3-benzoxazol-2(3H)-ones and their use as a medicament, preferably as a dermatologic agent, and as a cosmetic. These novel compounds are particularly useful in treating and/or preventing inflammation, irritation, itching, pruritus, pain, oedema and/or pro-allergic or allergic conditions in a patient. Usually they are topically applied to the skin or mucosa in the form of a pharmaceutical or cosmetic composition comprising the compound and a pharmaceutically and/or cosmetically acceptable carrier.

  本发明涉及一种新型的1,3-苯并噁唑-2(3H)-酮类化合物及其作为药物的用途，尤其是作为皮肤科药剂和化妆品的用途。这些新型化合物在治疗和/或预防患者的炎症、刺激、瘙痒、瘙痒、疼痛、水肿和/或过敏症状方面特别有用。通常它们以药用或化妆品组合物的形式局部应用于皮肤或黏膜，包括该化合物和一种药学和/或化妆学可接受的载体。
• 4-ACYLAMINOPYRAZOLE DERIVATIVES
  申请人：Sankyo Company, Limited

  公开号：EP1329160A2

  公开（公告）日：2003-07-23

  A 4-acylaminopyrazole derivative represented by the following general formula: wherein R1 is a hydrogen atom, an optionally substituted C1-C16 alkyl group or the like,    R2 and R3 are independently a hydrogen atom, a halogen atom, an optionally substituted C1-C6 alkyl group or the like, R4 is a hydrogen atom, a C1-C6 alkyl group or a cyano group, Z is an oxygen atom or a sulfur atom, Ar is an optionally substituted C6-C14 aryl group or an optionally substituted 5-6 membered unsaturated heterocyclic group, B is a hydrogen atom, a halogen atom, an optionally substituted C1-C16 alkyl group or the like.

  由以下通式代表的 4-酰氨基吡唑衍生物： 其中 R1 是氢原子、任选取代的 C1-C16 烷基或类似基团、 R2 和 R3 独立地为氢原子、卤素原子、任选取代的 C1-C6 烷基或类似基团、 R4 是氢原子、C1-C6 烷基或氰基、 Z 是氧原子或硫原子、 Ar 是任选取代的 C6-C14 芳基或任选取代的 5-6 位元不饱和杂环基团、 B 是氢原子、卤素原子、任选取代的 C1-C16 烷基或类似基团。
• Verfahren zur Herstellung von 4,5,6-Trichlorpyrimidin
  申请人：BAYER AG

  公开号：EP0377905B1

  公开（公告）日：1994-02-16
• VERFAHREN ZUR HERSTELLUNG VON 4,5,6-TRICHLOR- UND 2,4,5,6-TETRACHLORPYRIMIDIN
  申请人：BAYER AG

  公开号：EP0906289A1

  公开（公告）日：1999-04-07