Methyl-2-hexylnonanoat | 56363-65-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Methyl-2-hexylnonanoat
• 英文别名: Methyl 2-hexylnonanoate
• CAS: 56363-65-6
• 化学式: C₁₆H₃₂O₂
• 分子量: 256.429
• InChiKey: JZVYXHUEULQNHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Methyl-2-hexylnonanoat 生成 Methyl-<2-hexyl-2-hydroperoxy>-nonanoat
  参考文献：
  名称：

  .alpha.-Anions. VII. Direct oxidation of enolate anions to 2-hydroperoxy- and 2-hydroxycarboxylic acids and esters

  摘要：

  DOI：

  10.1021/jo00910a020

文献信息

• Heterocyclylamines as PI3K inhibitors
  申请人：Incyte Corporation

  公开号：US10376513B2

  公开（公告）日：2019-08-13

  The present invention provides heterocyclylamine derivatives of Formula I: wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.

  本发明提供了式 I 的杂环胺衍生物： 的杂环胺衍生物，其调节磷酸肌醇 3- 激酶 (PI3K) 的活性，可用于治疗与 PI3K 活性有关的疾病，例如炎症性疾病、免疫性疾病、癌症和其它疾病。
• Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease
  申请人：The Regents of the University of California

  公开号：US10889556B2

  公开（公告）日：2021-01-12

  There are provided inter alia metalloenzyme inhibitors, such as inhibitors of influenza A RNA dependent RNA polymerase PA subunit endonuclease, and methods of synthesis and use of the same.

  除其他外，还提供了金属酶抑制剂，例如甲型流感 RNA 依赖性 RNA 聚合酶 PA 亚基内切酶抑制剂，以及合成和使用这些抑制剂的方法。
• COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE
  申请人：The Regents of the University of California

  公开号：US20190106398A1

  公开（公告）日：2019-04-11

  There are provided inter alia metalloenzyme inhibitors, such as inhibitors of influenza A RNA dependent RNA polymerase PA subunit endonuclease, and methods of synthesis and use of the same.
• HETEROCYCLYLAMINES AS PI3K INHIBITORS
  申请人：Incyte Corporation

  公开号：US20190298724A1

  公开（公告）日：2019-10-03

  The present invention provides heterocyclylamine derivatives of Formula I: wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
• US9585965B2
  申请人：——

  公开号：US9585965B2

  公开（公告）日：2017-03-07