bis(4-Ethyloxyphenyl) carbohydrazide | 29639-08-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(4-Ethyloxyphenyl) carbohydrazide
• 英文别名: 1,5-Bis-(4-ethoxyphenyl)-carbohydrazid；1,3-Bis[(4-ethyloxyphenyl)amino]urea；1,3-bis(4-ethoxyanilino)urea
• CAS: 29639-08-5
• 化学式: C₁₇H₂₂N₄O₃
• 分子量: 330.387
• InChiKey: IUEYAFHNFZCWSR-UHFFFAOYSA-N

物化性质

• 密度：
  1.230±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  83.6
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  bis(4-Ethyloxyphenyl) carbohydrazide 在 三氯化铁 作用下， 以 硫酸 、 丙酮 为溶剂， 以96%的产率得到bis(4-ethoxyphenyl) carbodiazone
  参考文献：
  名称：

  从芳基取代的碳酰肼制备羰基重氮化合物的简便方法

  摘要：

  摘要 报道了一种制备双（取代苯基）碳重氮化合物（ArN=NCON=NAr）的简单新方法。在酸性介质中，通过芳基取代的卡巴肼与氯化铁氧化合成了九种化合物，收率良好。

  DOI：

  10.1080/00397919808007046

文献信息

• An Efficient Solid-Phase Method for the Preparation of Diaryl Carbazones
  作者：Hong Wang、Yu-Lu Wang、Geng Zhang、Jian-Ping Li、Xiao-Yang Wang

  DOI：10.1080/00397910008087170

  日期：2000.4

  Abstract The preparation of diaryl carbazones on solid-phase is reported for the first time. Using Fe(NO3)3.9H2O as oxidant, seven diaryl carbazones have been synthesized under mild conditions in excellent yields. The method is convenient and efficient.

  摘要 首次报道了固相法制备二芳基卡巴腙。使用 Fe(NO3)3.9H2O 作为氧化剂，在温和的条件下以优异的产率合成了七种二芳基碳腙。该方法方便有效。
• A SIMPLE, EFFICIENT, AND NEW CATALYST OXIDATION METHOD WITH KClO₃/H₂SO₄/FeSO₄FOR PREPARING BISAZO COMPOUNDS
  作者：Lei Shi、Feng Pan、XueShun Jia、YuLu Wang

  DOI：10.1081/scc-100103988

  日期：2001.1

  Using potassium chlorate, sulfuric acid and ferrous sulfate as a catalytic oxidation system to oxidize the aryl substituted carbazide to prepare new type bisazo compounds in one phase have been described for the first time in this paper. Eight bisaryl carbodiazones have been synthesized in high yields under mild conditions. A possible mechanism has been suggested.

  本文首次描述了以氯酸钾、硫酸和硫酸亚铁为催化氧化体系，氧化芳基取代卡巴肼，制备新型单相双偶氮化合物。已在温和条件下以高产率合成了八种双芳基碳重氮化合物。已经提出了一种可能的机制。
• Two-Phase Dehydrogenation of Aryl Substituted Carbazide Compounds
  作者：Yulu Wang、Chengjie Ru、Jianping Li、Hong Wang、Donglan Ma

  DOI：10.1080/00397919408010178

  日期：1994.6

  Abstract Two-phase dehydrogenation, which is a new reaction of aryl substituted carbazide compounds, is described in this paper. Ten new azo compounds were synthesized by the reaction of aryl substituted carbazide compounds with a phenoxyl radical between two phases in good yields.

  摘要 本文描述了芳基取代的卡巴肼化合物的新反应——两相脱氢反应。通过芳基取代的卡巴肼化合物与苯氧基自由基在两相之间以良好的产率反应合成了十种新的偶氮化合物。
• The Application of Ceric Ammonium Nitrate in the Synthesis of Carbodiazones
  作者：Jun-Ping Xiao、Yu-Lu Wang、Xue-Shun Jia、Xiao-Yang Wang、Hong Wang

  DOI：10.1080/00397910008087226

  日期：2000.4

  Abstract The preparation of bisaryl carbodiazone compounds from the aryl substituted carbazides with Ceric Ammonium Nitrate (CAN) has been reported for the first time in excellent yields (80-91%). This method only needs simple instruments and short reaction time. A possible mechanism has been suggested.

  摘要 首次报道了用硝酸铈铵 (CAN) 从芳基取代的卡巴肼制备双芳基碳重氮化合物，收率极好 (80-91%)。这种方法只需要简单的仪器和很短的反应时间。已经提出了一种可能的机制。
• An Efficient and Convenient Procedure for Preparation of Diaryl Carbazone from aryl substituted carbazide
  作者：Yulu Wang、Lei Shi、Xueshun Jia、Feng Pan、Donglan Ma、Xiaoyang Wang

  DOI：10.1080/00397919908085734

  日期：1999.1.1

  A new facile method for the synthesis of diaryl carbazone (ArN=NCONHNHAr) from aryl substituted carbazide is described. Eight of the compounds were preparated by oxidation of aryl substituted carbazide with ferric chloride in acid medium at room tempreture in good yield.