Prostaglandin F2alpha 9-methyl ether | 79743-27-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Prostaglandin F2alpha 9-methyl ether
• 英文别名: (Z)-7-[(1R,2R,3R,5S)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-methoxycyclopentyl]hept-5-enoic acid
• CAS: 79743-27-4
• 化学式: C₂₁H₃₆O₅
• 分子量: 368.5
• InChiKey: DHUJYNACDMVDIE-YNPSZXEPSA-N

物化性质

• 沸点：
  512.8±50.0 °C(Predicted)
• 密度：
  1.08±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  26
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT
  申请人：POLYACTIVA PTY LTD

  公开号：US20170216308A1

  公开（公告）日：2017-08-03

  The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, .beta.-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.