2-methyl-2H-thieno[3,2-c]pyrazole | 70820-69-8

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: 2-methyl-2H-thieno[3,2-c]pyrazole
• 英文别名: 2-Methylthieno[3,2-c]pyrazole
• CAS: 70820-69-8
• 化学式: C₆H₆N₂S
• 分子量: 138.193
• InChiKey: YOEOQXVQCZQHAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  46.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• HETEROCYCLE DERIVATIVES AS PESTICIDES
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20190021329A1

  公开（公告）日：2019-01-24

  The invention relates to novel compounds of the formula (I) in which R 1 , R 2 , R 3 , A 1 , X and n have the meanings given above, to the use thereof as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for the preparation thereof.

  该发明涉及公式（I）的新化合物，其中R1，R2，R3，A1，X和n具有上述给定的含义，用作杀虫剂和/或杀虫剂以控制动物害虫，并且涉及其制备的过程和中间体。
• SUBSTITUTED 6-AZA-ISOINDOLIN-1-ONE DERIVATIVES
  申请人：Adams Mark E.

  公开号：US20140206680A1

  公开（公告）日：2014-07-24

  Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, p, R 1 , R 2 , R 3a , R 4 , and R 5 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, cancer, and other disorders, diseases, and conditions for which inhibition of SYK is indicated.

  本发明涉及公式1的化合物及其药学上可接受的盐，其中G、p、R1、R2、R3a、R4和R5在说明书中有定义。本发明还涉及制备公式1化合物的材料和方法，包括含有它们的制药组合物，以及它们用于治疗涉及免疫系统和炎症的紊乱、疾病和状况，包括类风湿性关节炎、癌症和其他需要抑制SYK的紊乱、疾病和状况。
• [EN] COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES<br/>[FR] COMPOSÉS DE LIAISON À CDK2 COVALENTS UTILISÉS À DES FINS THÉRAPEUTIQUES
  申请人：UMBRA THERAPEUTICS INC

  公开号：WO2022187693A1

  公开（公告）日：2022-09-09

  Heteroaryl sulfonyl compounds and compositions that have a CDK2 Recognition Moiety bound to an electrophile for the selective covalent modification of CDK2 to treat CDK2-mediated disorders are described.

  本文描述了具有CDK2识别基团结合到亲电体的杂环磺酰化合物和组合物，用于选择性共价修饰CDK2以治疗CDK2介导的疾病。
• Heterocycle derivatives as pesticides
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US10375962B2

  公开（公告）日：2019-08-13

  The invention relates to novel compounds of the formula (I) in which R1, R2, R3, A1, X and n have the meanings given above, to the use thereof as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for the preparation thereof.

  本发明涉及式 (I) 的新型化合物 其中 R1、R2、R3、A1、X 和 n 具有上述含义、 用作控制动物害虫的杀螨剂和/或杀虫剂，以及用于制备的工艺和中间体。
• US9056873B2
  申请人：——

  公开号：US9056873B2

  公开（公告）日：2015-06-16