4-[4-(6-fluoro-9-methylsulfonyloxy-1,5-dihydro-3H-2,4-benzodioxepin-3-yl)-2-thiazolyl]-1-[2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]piperidine | 1879929-70-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 4-[4-(6-fluoro-9-methylsulfonyloxy-1,5-dihydro-3H-2,4-benzodioxepin-3-yl)-2-thiazolyl]-1-[2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]piperidine
• 英文别名: [6-Fluoro-3-[2-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-9-yl] methanesulfonate
• CAS: 1879929-70-0
• 化学式: C₂₅H₂₆F₄N₄O₆S₂
• 分子量: 618.63
• InChiKey: UYWFLHVJGRXRHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  41
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  150
• 氢给体数：
  0
• 氢受体数：
  13

文献信息

• [EN] ACTIVE COMPOUND COMBINATIONS<br/>[FR] COMBINAISONS DE COMPOSÉS ACTIFS
  申请人：BAYER AG

  公开号：WO2021239766A1

  公开（公告）日：2021-12-02

  The present invention relates to active compound combinations, in particular within a fungicide composition, which comprise as compound (A) a compound of formula (I) and as compound (B) a further fungicidally active compound as specified below. Moreover, the invention relates to compositions comprising such compound combination and to the use of the compound combinations and the fungicide compositions as biologically active agent, especially for control of phytopathogenic fungi in crop protection and in the protection of industrial materials and as plant growth regulators.

  本发明涉及活性化合物组合，特别是在杀菌剂组合中，其中包括化合物（A）为式（I）的化合物，以及化合物（B）为下文规定的另一种具有杀菌活性的化合物。此外，本发明涉及包含这种化合物组合的组合物以及将这种化合物组合和杀菌剂组合用作生物活性剂的用途，特别是用于控制作物保护中的植物病原真菌和工业材料保护以及作为植物生长调节剂。
• PROCESS FOR PREPARING 1, 2-BENZENEDIMETHANOL COMPOUND
  申请人：GOWAN COMPANY, L.L.C.

  公开号：US20200399263A1

  公开（公告）日：2020-12-24

  A process for preparing a compound represented by Formula [1], the process comprising a step of hydrolyzing a compound represented by Formula [2] under an acidic or basic condition, and a step of reacting a compound represented by Formula [3] with a metal acetate salt, and a step of halogenating a compound represented by Formula [4]; a process for preparing a compound represented by Formula [1] comprising a step of reacting a compound represented by Formula [3] with a metal acetate salt, and then, adding alcohol, water, or base to the reaction solution to perform reaction; a process for preparing a compound represented by Formula [1] comprising a step of reacting a compound represented by Formula [3] under a presence or absence of a base, an ionic liquid and a metal sulfate salt, in water or a mixed solvent of water and an organic solvent; a compound represented by Formula [2] or a salt of the same; and a compound represented by Formula [3] or a salt of the same.

  制备由化学式[1]表示的化合物的方法，包括在酸性或碱性条件下水解由化学式[2]表示的化合物的步骤，以及与金属醋酸盐反应由化学式[3]表示的化合物的步骤，以及卤代由化学式[4]表示的化合物的步骤；制备由化学式[1]表示的化合物的方法，包括将由化学式[3]表示的化合物与金属醋酸盐反应的步骤，然后向反应溶液中加入醇、水或碱来进行反应；制备由化学式[1]表示的化合物的方法，包括在水或水和有机溶剂的混合溶剂中，在存在或缺乏碱、离子液体和金属硫酸盐的情况下，将由化学式[3]表示的化合物进行反应的步骤；由化学式[2]表示的化合物或其盐；以及由化学式[3]表示的化合物或其盐。
• [EN] AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES<br/>[FR] HÉTÉROCYCLES À SUBSTITUTION AZABICYCLYLE UTILISÉS COMME FONGICIDES
  申请人：BAYER AG

  公开号：WO2021249995A1

  公开（公告）日：2021-12-16

  The present disclosure relates to azabicyclyl-substituted heterocyclic compounds of formula (I), wherein A1, A2, m, R3, R4, R5, L, R6, T, the ring Y, p, R7 and Q have the meanings as defined in the specification, to compositions comprising such compounds, to processes and intermediates for their preparation as well as the uses thereof for controlling phytopathogenic microorganisms, such as phytopathogenic fungi.

  本公开涉及式(I)的含氮杂环取代杂环化合物，其中A1、A2、m、R3、R4、R5、L、R6、T、环Y、p、R7和Q的含义如规范中定义的那样，以及包含这种化合物的组合物、用于其制备的过程和中间体，以及用于控制植物病原微生物（如植物病原真菌）的用途。
• FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM
  申请人：SDS BIOTECH K.K.

  公开号：US20170231226A1

  公开（公告）日：2017-08-17

  The invention relates to a compound or a salt thereof of formula [1], a fungicidal composition containing the compound or a salt thereof, a method for controlling plant disease occurring from phytopathogenic microorganism including the step of applying the fungicidal composition and a production method of the compound.

  该发明涉及一种具有化学式[1]的化合物或其盐，包含该化合物或其盐的杀菌组合物，一种控制由植物病原微生物引起的植物病害的方法，包括应用杀菌组合物的步骤，以及该化合物的生产方法。
• [EN] 1,3,4-OXADIAZOLE PYRIMIDINES AS FUNGICIDES<br/>[FR] 1,3,4-OXADIAZOLE PYRIMIDINES EN TANT QUE FONGICIDES
  申请人：BAYER AG

  公开号：WO2021255169A1

  公开（公告）日：2021-12-23

  The present invention relates to 1,3,4-oxadiazole pyrimidine compounds, processes and intermediates for 5 their preparation as well as the uses thereof for controlling phytopathogenic microorganisms, such as phytopathogenic fungi.

  本发明涉及1,3,4-噁二唑嘧啶化合物、其制备过程和中间体，以及它们在控制植物病原微生物（如植物病原真菌）方面的用途。