Glutathion-L-Arginin-Salz | 21867-05-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Glutathion-L-Arginin-Salz
• 英文别名: H-DL-gGlu-DL-Cys-Gly-OH.H-Arg-OH；2-amino-5-[[1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid;(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid
• CAS: 21867-05-0
• 化学式: C₆H₁₄N₄O₂*C₁₀H₁₇N₃O₆S
• 分子量: 481.53
• InChiKey: FADLIXHQWBEYBF-VWMHFEHESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.54
• 重原子数：
  32
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  288
• 氢给体数：
  10
• 氢受体数：
  12

文献信息

• SOLUTONS FOR INCREASING THE STABILITY AND SHELF LIFE OF AN ORGAN TISSUE PRESERVATION SOLUTION
  申请人：Somahlution, LLC

  公开号：EP3027016A1

  公开（公告）日：2016-06-08
• SOLUTIONS FOR INCREASING THE STABILITY AND SHELF LIFE OF AN ORGAN AND TISSUE PRESERVATION SOLUTION
  申请人：SOMAHLUTION, LLC

  公开号：US20160249603A1

  公开（公告）日：2016-09-01

  Organ and tissue preservation solutions having improved stability are disclosed. The solutions are comprised of two separate solutions. The first solution, Solution A, is comprised of a balanced salt solution that is stable in solution at a pH of 7.0 or above. A second solution, Solution B, is comprised of an aqueous solution containing L-glutathione and/or cysteinylglycine, a sugar such as D-glucose, L-Arginine, a reducing agent such as ascorbic acid and water at a pH of below 7.0, preferably from about 3.0 to 5.0. The two Solutions are then mixed together at the point of use and the pH adjusted to about 7.3 resulting in the organ and tissue preservation solution having improved stability. Preferably, solution A has a pH of about 7.6 and solution B has a pH of about 5.0. The present invention is also comprised of kits 20 that contain the two Solutions in two separate containers 22, 24 . In an alternate embodiment, the sugar can be in Solution A.
• [EN] SOLUTONS FOR INCREASING THE STABILITY AND SHELF LIFE OF AN ORGAN TISSUE PRESERVATION SOLUTION<br/>[FR] SOLUTIONS POUR AUGMENTER LA STABILITÉ ET LA DURÉE DE VIE EN STOCKAGE D'UNE SOLUTION DE CONSERVATION D'ORGANE ET DE TISSU
  申请人：SOMAHLUTION LLC

  公开号：WO2015077199A1

  公开（公告）日：2015-05-28

  Organ and tissue preservation solutions having improved stability are disclosed. The solutions are comprised of two separate solutions. The first solution, Solution A, is comprised of a balanced salt solution that is stable in solution at a pH of 7.0 or above. A second solution, Solution B, is comprised of an aqueous solution containing L-glutathione and/or cysteinylglycine, a sugar such as D-glucose, L-Arginine, a reducing agent such as ascorbic acid and water at a pH of below 7.0, preferably from about 3.0 to 5.0. The two Solutions are then mixed together at the point of use and the pH adjusted to about 7.3 resulting in the organ and tissue preservation solution having improved stability. Preferably, solution A has a pH of about 7.6 and solution B has a pH of about 5.0. The present invention is also comprised of kits 20 that contain the two Solutions in two separate containers 22, 24. In an alternate embodiment, the sugar can be in Solution A.