(3R,4S,5S,6R)-2-heptadecoxy-6-(hydroxymethyl)oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (3R,4S,5S,6R)-2-heptadecoxy-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₂₃H₄₆O₆
• 分子量: 418.6
• InChiKey: WPEOSFDPNQGBCR-HZQGQDIUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  29
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• ANTI-WRINKLE AGENT AND ADAM INHIBITOR
  申请人：Shiseido Company, Ltd.

  公开号：EP2127636A1

  公开（公告）日：2009-12-02

  Disclosed is an anti-wrinkle agent for ameliorating a wrinkle (particularly a fine wrinkle) developed when the barrier function is decreased by dryness and the like. Also disclosed is an ADAM inhibitor. The anti-wrinkle agent or the ADAM inhibitor comprises an alkyl glucoside represented by the general formula: (1) [wherein R represents a linear or branched alkyl group having 1 to 18 carbon atoms] or a salt thereof.

  本发明公开了一种抗皱剂，用于改善因干燥等原因导致屏障功能降低时产生的皱纹（尤其是细小皱纹）。还公开了一种 ADAM 抑制剂。抗皱剂或 ADAM 抑制剂包括由通式表示的烷基葡萄糖苷：(1) [其中 R 代表具有 1 至 18 个碳原子的直链或支链烷基]或其盐。
• COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPIOID OVERDOSE
  申请人：Opiant Pharmaceuticals, Inc.

  公开号：US20220387306A1

  公开（公告）日：2022-12-08

  Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising nalmefene are provided. Methods of treating opioid overdose with the drug products are also provided.