Nonaethylene glycol p-nonylphenyl ether phosphate | 59415-87-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: Nonaethylene glycol p-nonylphenyl ether phosphate
• 英文别名: 2-[2-[2-[2-[2-[2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl dihydrogen phosphate
• CAS: 59415-87-1
• 化学式: C₃₃H₆₁O₁₃P
• 分子量: 696.8
• InChiKey: RDAPNZKBXOEJME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  47
• 可旋转键数：
  37
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  150
• 氢给体数：
  2
• 氢受体数：
  13

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• Improved device and method of separating and assaying whole blood
  申请人：Bayer Corporation

  公开号：EP0535485A1

  公开（公告）日：1993-04-07

  An improved device and method of separating the cellular components of whole blood from plasma or serum and assaying the plasma or serum for a predetermined soluble constituent are disclosed. The device includes a filter pad, that separates the cellular components of whole blood from the serum or plasma, and a test pad, that assays the serum or plasma for a predetermined soluble constituent. The filter pad effectively separates and retains cellular components of the whole blood sample, thereby eliminating assay interference by the cellular components of whole blood. The method includes contacting the whole blood with a test device including a filter pad comprising a suitable carrier matrix homogeneously incorporating therein a separating reagent composition comprising a) separating reagent, like an agglutinin, such as a blood type nonspecific lectin; a coagulant, such as a thrombin or a thrombin-like compound; or a mixture thereof, and b) a nonhemolytic surfactant, like an ethoxylated or propoxylated nonionic or anionic surfactant, such that the cellular components of the whole blood are separated from the plasma or serum as the blood permeates through the filter pad, The essentially cell-free plasma or serum then saturates a test pad that is in contact with the filter pad. After the plasma or serum saturates the test pad, the test pad is examined for a qualitative or quantitative response to a predetermined soluble constituent of the whole blood.

  本发明公开了一种从血浆或血清中分离全血细胞成分并检测血浆或血清中预定可溶性成分的改进装置和方法。该装置包括一个过滤垫，用于将全血的细胞成分从血清或血浆中分离出来；以及一个测试垫，用于检测血清或血浆中的预定可溶性成分。过滤垫可有效分离并保留全血样本中的细胞成分，从而消除全血细胞成分对检测的干扰。该方法包括将全血与测试装置接触，测试装置包括一个过滤垫，过滤垫由合适的载体基质组成，其中均匀地加入了分离试剂组合物，分离试剂组合物包括 a) 分离试剂，如凝集素，如血型非特异性凝集素；凝血剂，如凝血酶或凝血酶样化合物；或其混合物，以及 b) 非溶血性表面活性剂，如乙氧基化或丙氧基化的非离子或阴离子表面活性剂，这样，当血液渗透过滤垫时，全血中的细胞成分与血浆或血清分离。血浆或血清饱和到测试垫上后，测试垫会对全血中预定的可溶性成分进行定性或定量检测。
• A METHOD FOR ENHANCING THE COOLING EFFECT OF A COOLING COMPOUND
  申请人：Symrise AG

  公开号：EP3434330A1

  公开（公告）日：2019-01-30

  Suggested is a method for enhancing the cooling effect of a cooling substance on the skin or a mucous membrane encompassing the following steps: (a) providing specific polyols; (b) providing physiological cooling compounds; (c) blending said with said physiological cooling compounds, and (d) bringing said blend into contact with skin or mucous membranes.

  建议一种增强冷却物质对皮肤或粘膜的冷却效果的方法，包括以下步骤： (a) 提供特定的多元醇 (b) 提供生理性冷却化合物； (c) 将所述物质与所述生理性冷却化合物混合，以及 (d) 使所述混合物与皮肤或粘膜接触。
• Micro RNA isolation from biological fluid
  申请人：SIGMA-ALDRICH CO. LLC

  公开号：US10131902B2

  公开（公告）日：2018-11-20

  The present disclosure provides methods and kits for isolating miRNAs from biological fluids.

  本公开提供了从生物液体中分离 miRNA 的方法和试剂盒。