1-(But-2-yn-1-yl)cyclopentane-1-carboxylic acid | 89056-31-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-(But-2-yn-1-yl)cyclopentane-1-carboxylic acid
• 英文别名: 1-but-2-ynylcyclopentane-1-carboxylic acid
• CAS: 89056-31-5
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: NMIBFWMSKZDRPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• INDOLIZINE INHIBITORS OF LEUKOTRIENE PRODUCTION
  申请人：Boehringer Ingelheim International GmbH

  公开号：EP2331541A1

  公开（公告）日：2011-06-15
• [EN] INDOLIZINE INHIBITORS OF LEUKOTRIENE PRODUCTION<br/>[FR] INHIBITEURS INDOLIZINE DE LA PRODUCTION DE LEUKOTRIÈNES
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2010027762A1

  公开（公告）日：2010-03-11

  The present invention relates to compounds of formula I and pharmaceutically acceptable salt thereof, wherein X1 to X4, R1 to R4, A, B, D and m are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.