L-Histidine, 2-hydroxyethyl ester | 86150-62-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: L-Histidine, 2-hydroxyethyl ester
• 英文别名: 2-hydroxyethyl (2S)-2-amino-3-(1H-imidazol-5-yl)propanoate
• CAS: 86150-62-1
• 化学式: C₈H₁₃N₃O₃
• 分子量: 199.21
• InChiKey: PFULGCLBYIDEMO-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  101
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Functionalized fluorescent nanocrystals, and methods for their preparation and use
  申请人：Molecular Probes, Inc.

  公开号：EP2305775A2

  公开（公告）日：2011-04-06

  Functionalized fluorescent nanocrystal compositions and methods for making and using these compositions are disclosed. The compositions are fluorescent nanocrystals coated with at least one material. The coating material has chemical compounds or ligands with functional groups or moieties with conjugated electrons and moieties for imparting solubility to coated fluorescent nanocrystals in aqueous solutions. The coating material provides for functionalized fluorescent nanocrystal compositions which are water soluble, chemically stable, and emit light with a high quantum yield and/or luminescence efficiency when excited with light. The coating material may also have chemical compounds or ligands with moieties for bonding to target molecules and cells as well as moieties for cross-linking the coating. In the presence of reagents suitable for reacting to form capping layers, the compounds in the coating may form a capping layer on the fluorescent nanocrystal with the coating compounds operably bonded to the capping layer.

  公开了功能化荧光纳米晶体组合物以及制造和使用这些组合物的方法。这些组合物是涂有至少一种材料的荧光纳米晶体。涂层材料具有带有共轭电子的官能团或分子的化合物或配体，以及用于赋予涂层荧光纳米晶体在水溶液中溶解性的分子。涂层材料提供的功能化荧光纳米晶体组合物可溶于水，化学性质稳定，在光的激发下可发出高量子产率和/或发光效率的光。涂层材料中还可能含有与目标分子和细胞结合的化合物或配体，以及交联涂层的分子。在适用于反应形成封盖层的试剂存在时，涂层中的化合物可在荧光纳米晶体上形成封盖层，涂层化合物与封盖层可操作地结合在一起。
• [EN] FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING<br/>[FR] MARQUEURS PL FLUORESCENTS POUR DES SÉPARATIONS PAR FOCALISATION ISOÉLECTRIQUE ET LE MARQUAGE FLUORESCENT
  申请人：VIGH GYULA

  公开号：WO2013033046A2

  公开（公告）日：2013-03-07

  UV-Absorbing and fluorescent pl markers for isoelectric focusing separations and fluorescent labeling, and methods for making and using the markers.