(S)-2-(Diethylamino)butanoic acid | 1007885-58-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-(Diethylamino)butanoic acid
• 英文别名: (2S)-2-(diethylamino)butanoic acid
• CAS: 1007885-58-6
• 化学式: C₈H₁₇NO₂
• 分子量: 159.228
• InChiKey: WXZZJKVGEJBSJP-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] PRODRUGS OF 17β-HSD1 -INHIBITORS<br/>[FR] PROMÉDICAMENTS D'INHIBITEURS DE 17Β-HSD1
  申请人：FORENDO PHARMA LTD

  公开号：WO2016102775A1

  公开（公告）日：2016-06-30

  The present invention accordingly provides novel compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in the claims. The invention further relates to their in treatment or prevention of steroid hormone dependent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of the 17β-HSD1 enzyme and/or requiring the lowering of the endogenous estradiol concentration.

  本发明提供了式（I）的新化合物，其中R1、R2、R3和R4如权利要求中所定义。该发明还涉及它们在治疗或预防类固醇激素依赖性疾病或紊乱方面的应用，例如需要抑制17β-HSD1酶或需要降低内源性雌二醇浓度的类固醇激素依赖性疾病或紊乱。
• PHARMACEUTICAL COMPOUND
  申请人：VALLAURIX PTE. LTD.

  公开号：EP3088417A1

  公开（公告）日：2016-11-02

  The present invention relates to compounds comprising a quaternary ammonium group, their use in skin diseases, and their preparation.

  本发明涉及包含季铵基团的化合物、其在皮肤病中的用途及其制备方法。
• INK SET AND RECORDING METHOD
  申请人：Seiko Epson Corporation

  公开号：EP3543301A1

  公开（公告）日：2019-09-25

  An ink set includes a first ink and a second ink which are water-based ink compositions, in which each of the first ink and the second ink includes a pigment and resin including resin particles, the first ink includes a first pigment and the second ink includes a second pigment different from the first pigment, the first ink and the second ink are mixed with a 5% by mass water-based solution of magnesium sulfate heptahydrate to increase a volume average particle diameter of the ink and a difference in the volume average particle diameter for the inks in the inks after mixing is 40% or less, and the ink set is used for recording together with a treatment liquid including an aggregating agent for aggregating the components of the water-based ink compositions.

  一套油墨包括第一种油墨和第二种油墨，它们都是水基油墨组合物，其中第一种油墨和第二种油墨都包括颜料和包括树脂颗粒的树脂，第一种油墨包括第一种颜料，第二种油墨包括与第一种颜料不同的第二种颜料、将第一墨水和第二墨水与质量分数为 5%的七水硫酸镁水基溶液混合，以增加墨水的体积平均颗粒直径，混合后墨水中墨水的体积平均颗粒直径的差值为 40% 或更小，墨水组与包括聚合剂的处理液一起用于记录，聚合剂用于聚合水基墨水组合物的组分。
• PRINTING METHOD AND WHITE INK COMPOSITION
  申请人：Seiko Epson Corporation

  公开号：EP3536512A1

  公开（公告）日：2019-09-11

  A printing method is provided. The printing method includes applying a treatment liquid containing a flocculant operable to flocculate at least one constituent of an ink composition onto a printing medium, and applying at least one ink composition including a white ink composition containing a white coloring material and resin particles onto the printing medium. The volume average particle size of the resin particles varies 50% or less when the white ink composition is mixed with the treatment liquid.

  提供了一种印刷方法。该印刷方法包括将含有可絮凝油墨组合物中至少一种成分的絮凝剂的处理液涂抹到印刷介质上，并将至少一种油墨组合物涂抹到印刷介质上，该油墨组合物包括含有白色着色材料和树脂颗粒的白色油墨组合物。当白色油墨组合物与处理液混合时，树脂颗粒的体积平均粒度变化不超过 50%。
• Reaction solution and ink jet recording method
  申请人：Seiko Epson Corporation

  公开号：US10245847B2

  公开（公告）日：2019-04-02

  Provided is a reaction solution containing any one or more kinds of organic solvents from esters, alkylene glycol ethers, cyclic esters, and alkoxyalkyl amides; and an aggregating agent which aggregates components of an ink composition, in which the reaction solution is used for a recording method performed by using the ink composition.

  本发明提供了一种反应溶液，其中含有酯类、亚烷基乙二醇醚类、环酯类和烷氧基烷基酰胺中的一种或多种有机溶剂；以及一种聚合剂，该聚合剂可聚合油墨组合物中的成分，其中该反应溶液用于使用该油墨组合物进行的记录方法。