N^α,N^α-Dimethyl-N-^δ-lauroyl-DL-ornithin | 17196-46-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N^α,N^α-Dimethyl-N-^δ-lauroyl-DL-ornithin
• 英文别名: 2-(Dimethylamino)-5-(dodecanoylamino)pentanoic acid
• CAS: 17196-46-2
• 化学式: C₁₉H₃₈N₂O₃
• 分子量: 342.522
• InChiKey: GBCGWCPXLXEHQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  24
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  69.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• S-ADENOSYLMETHIONINE FORMULATIONS WITH ENHANCED BIOAVAILABILITY
  申请人：MacDonald I. David

  公开号：US20130142847A1

  公开（公告）日：2013-06-06

  Provided herein are compositions and methods to enhance the absorption of S-adenosylmethionine (SAMe) and methods of treating various disorders or diseases using non-parenteral SAMe formulations with enhanced-absorption and improved bioavailability. In certain embodiments, the enhanced bioavailability formulations provided herein may be used to treat a variety of diseases or disorders, such as for example, psychiatric disorders including, generalized anxiety disorder, obsessive compulsive disorder, post traumatic stress disorder, panic disorder, depressive disorders (e.g. major clinical depression) and dysthymia; as well as treating liver disorders, cancer, autoimmune disorders, inflammatory disorders, joint disorders, gastrointestinal disorders and cardiovascular disease.
• US4279891A
  申请人：——

  公开号：US4279891A

  公开（公告）日：1981-07-21