3-(methoxy-5-chlorotricyclo[3.3.1.13,7 ]dec-2-ylidenemethyl)-phenol | 142849-65-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(methoxy-5-chlorotricyclo[3.3.1.13,7 ]dec-2-ylidenemethyl)-phenol
• 英文别名: 3-(Methoxy-5-chlorotricyclo[3.3.1.13,7 ]dec-2-ylidenemethyl)phenol
• CAS: 142849-65-8
• 化学式: C₁₈H₂₁ClO₂
• 分子量: 304.817
• InChiKey: PPXPOVNVRVOIQZ-MSUUIHNZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.57
• 重原子数：
  21.0
• 可旋转键数：
  2.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  29.46
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  3-(methoxy-5-chlorotricyclo[3.3.1.13,7 ]dec-2-ylidenemethyl)-phenol 在 N-碘代丁二酰亚胺 作用下， 以 甲苯 为溶剂， 以9.3 g的产率得到
  参考文献：
  名称：

  COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE

  摘要：

  Disclosed is a compound represented by formula [I] according to the specification, or a salt thereof, a composition comprising the compound, a chemiluminescence method using the compound, a method for measuring chemiluminescence signal, a reagent comprising the compound, a reagent kit comprising the compound and a method for assaying analyte.

  公开号：

  US20230242499A1
• 作为产物：
  描述：

  在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 以100 %的产率得到3-(methoxy-5-chlorotricyclo[3.3.1.13,7 ]dec-2-ylidenemethyl)-phenol
  参考文献：
  名称：

  COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE

  摘要：

  Disclosed is a compound represented by formula [I] according to the specification, or a salt thereof, a composition comprising the compound, a chemiluminescence method using the compound, a method for measuring chemiluminescence signal, a reagent comprising the compound, a reagent kit comprising the compound and a method for assaying analyte.

  公开号：

  US20230242499A1

文献信息

• [EN] CHEMILUMINESCENT COMPOSITIONS, METHODS, ASSAYS AND KITS FOR OXIDATIVE ENZYMES<br/>[FR] COMPOSITIONS CHIMIOLUMINESCENTES, PROCÉDÉS, DOSAGES ET KITS POUR ENZYMES OXYDATIVES
  申请人：LIFE TECHNOLOGIES CORP

  公开号：WO2010101839A3

  公开（公告）日：2011-01-13
• CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES
  申请人：TROPIX, INC.

  公开号：EP0497972B1

  公开（公告）日：1998-12-23
• CHEMILUMINESCENT COMPOSITIONS, METHODS, ASSAYS AND KITS FOR OXIDATIVE ENZYMES
  申请人：Juo Rouh-Rong

  公开号：US20120100566A1

  公开（公告）日：2012-04-26

  Chemiluminescent compositions, methods, assays and kits for oxidative enzymes are described. Further disclosed are dioxetane compounds of the form: 0-0 ΛR R R T (i) where R can independently be any branched alkyl or cycloalkyl group which provides stabilization for the dioxetane or where both R groups together form a cycloalkyl or polycycloalkyl moiety spiro bound to the dioxetane ring, wherein each R group or the spiro bound moiety can be unsubstituted or substituted with one or more electron-withdrawing groups or electron donating groups, or groups providing preferential oxidative isozyme substrate recognition, and wherein Ri is an aryl group, or an alkyl group of 1-20 carbon atoms, which can be optionally substituted with 1 or more halogen atoms, and wherein T is an aryl or heteroaryl ring capable of emitting light upon enzyme activated decomposition of the dioxetane I. Kits, methods and assays are also disclosed that comprise the dioxetane compounds.
• US9518285B2
  申请人：——

  公开号：US9518285B2

  公开（公告）日：2016-12-13
• US9856508B2
  申请人：——

  公开号：US9856508B2

  公开（公告）日：2018-01-02