Benzaldehyd-1-phenylpropylimid | 597522-31-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzaldehyd-1-phenylpropylimid
• CAS: 597522-31-1
• 化学式: C₁₆H₁₇N
• 分子量: 223.318
• InChiKey: KJPHMCIQMIYERV-GHRIWEEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.26
• 重原子数：
  17.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  12.36
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  Benzaldehyd-1-phenylpropylimid 以97%的产率得到
  参考文献：
  名称：

  Soloshonok Vadim A., Kirilenko Alexander G., Kukhar Valery P., Resnati Gu+, Tetrahedron Lett, 35 (1994) N 19, S 3119-3122

  摘要：

  DOI：
• 作为产物：
  描述：

  以84%的产率得到
  参考文献：
  名称：

  Soloshonok Vadim A., Kirilenko Alexander G., Kukhar Valery P., Resnati Gu+, Tetrahedron Lett, 35 (1994) N 19, S 3119-3122

  摘要：

  DOI：

文献信息

• Origin of 1, 3-induction in the addition of alkyl lithium to imines bearing an N-stereogenic center
  作者：Nancy、Soma Ghosh、Nishan Singh、Gurmeet Kaur Nanda、P. Venugopalan、Prasad V. Bharatam、Sanjay Trehan

  DOI：10.1039/b300478c

  日期：——

  The origin of diastereoselectivity in the addition of alkyl lithium to chiral Schiff bases has been investigated experimentally and theoretically and the formation of the major diastereomer can be explained from the energy minimized structure of the Schiff base in which the phenyl group has been found to orient in such a manner that it posed lesser steric hindrance to the incoming nucleophile as compared to the alkyl group

  实验和理论研究了烷基锂与手性席夫碱加成过程中非对映选择性的来源，主要非对映异构体的形成可以从席夫碱的能量最小化结构中得到解释。
• Wuerthwein, Ernst-Ullrich; Halim, Herman; Schwarz, Helmut, Chemische Berichte, 1982, vol. 115, # 7, p. 2626 - 2634
  作者：Wuerthwein, Ernst-Ullrich、Halim, Herman、Schwarz, Helmut、Nibbering, Nico M. M.

  DOI：——

  日期：——
• Gracheva, R. A.; Potapov, V. M.; Sivov, N. A., Journal of Organic Chemistry USSR (English Translation), 1981, vol. 17, p. 1963 - 1970
  作者：Gracheva, R. A.、Potapov, V. M.、Sivov, N. A.、Sivova, L. I.

  DOI：——

  日期：——
• A convenient synthesis of the paclitaxel side-chain via a diastereoselective Staudinger reaction
  作者：Stephen Brown、Allan M. Jordan、Nicholas J. Lawrence、Robin G. Pritchard、Alan T. McGown

  DOI：10.1016/s0040-4039(98)00548-6

  日期：1998.5

  The N-benzylidene derivative of (S)-(-)-1-(p-methoxyphenyl)propyl-1-amine, obtained by a new resolution procedure, exhibits moderate selectivity in the reaction with 2-acetoxyketene; the (S)-(-)-1-(p-methoxyphenyl)propyl group can be oxidatively cleaved from the resultant beta-lactam, an important precursor for taxane semi-synthesis. (C) 1998 Elsevier Science Ltd. All rights reserved.
• GRACHEVA, R. A.;POTAPOV, V. M.;SIVOV, N. A.;SIVOVA, L. I., ZH. ORGAN. XIMII, 1981, 17, N 10, 2201-2209
  作者：GRACHEVA, R. A.、POTAPOV, V. M.、SIVOV, N. A.、SIVOVA, L. I.

  DOI：——

  日期：——