(3-Butyl-3-ethyl-5-{3-[8-(4-{1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-oxoazetidin-2-yl}benzylamino)octanoylamino]phenyl}-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]thiepin-7-yl)dimethylammonium trifluoroacetate | 439114-26-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: (3-Butyl-3-ethyl-5-{3-[8-(4-{1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-oxoazetidin-2-yl}benzylamino)octanoylamino]phenyl}-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]thiepin-7-yl)dimethylammonium trifluoroacetate
• 英文别名: N-[3-[3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxo-4,5-dihydro-2H-1lambda6-benzothiepin-5-yl]phenyl]-8-[[4-[1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenyl]methylamino]octanamide;2,2,2-trifluoroacetic acid；N-[3-[3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxo-4,5-dihydro-2H-1λ6-benzothiepin-5-yl]phenyl]-8-[[4-[1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenyl]methylamino]octanamide;2,2,2-trifluoroacetic acid
• CAS: 439114-26-8
• 化学式: C₂HF₃O₂*C₅₇H₇₀F₂N₄O₆S
• 分子量: 1091.29
• InChiKey: MTNFTCZHPBSEHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.82
• 重原子数：
  77
• 可旋转键数：
  23
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  189
• 氢给体数：
  5
• 氢受体数：
  14

文献信息

• Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
  申请人：——

  公开号：US20020128252A1

  公开（公告）日：2002-09-12

  Compounds of the formula I, 1 in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.

  具有公式I,1的化合物，其中R1、R2、R3、R4、R5和R6的含义如描述中所述，并其生理上可接受的盐。这些化合物适用于用途，例如作为降脂药。