4-Oxo-hex-2-ensaeure | 83349-25-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: 4-Oxo-hex-2-ensaeure
• 英文别名: (Z)-4-oxohex-2-enoic acid
• CAS: 83349-25-1
• 化学式: C₆H₈O₃
• 分子量: 128.128
• InChiKey: VUZJJUOKMOGBDH-ARJAWSKDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  马来酸酐 在 盐酸 、 ethyl(triethylsiloxy)cadmium 、 ethyl(triethylsiloxy)zinc 、 ethyl(triphenylsiloxy)zinc 、 ethyl(triphenylsiloxy)cadmium 作用下， 以 甲苯 为溶剂， 反应 2.0h， 以72%的产率得到顺丁烯二酸
  参考文献：
  名称：

  Shnol', T. R.; Krasnov, Yu. N.; Galiulliana, R. F., Journal of general chemistry of the USSR, 1982, vol. 52, # 6, p. 1189 - 1194

  摘要：

  DOI：

文献信息

• PYRROLOTRIAZINE ANILINE PRODRUG COMPOUNDS USEFUL AS KINASE INHIBITORS
  申请人：Liu Chunjian

  公开号：US20070213300A1

  公开（公告）日：2007-09-13

  Compounds having the Formula (I), including pharmaceutically acceptable salts thereof, wherein at least one of X 1 , X 2 or X 3 is and any remaining X 1 , X 2 or X 3 is hydrogen, which are useful as kinase inhibitors, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , A 1 , A 2 and m are as described herein.

  具有化学式（I）的化合物，包括其药学上可接受的盐，其中X1、X2或X3中至少有一个是氢，其余的X1、X2或X3是氢，这些化合物可用作激酶抑制剂，其中R1、R2、R3、R4、R5、R6、A1、A2和m如本文所述。
• Intermediates Useful in the Preparation of Maleimide Functionalized Polymers
  申请人：McManus Samuel P.

  公开号：US20120004422A1

  公开（公告）日：2012-01-05

  Methods for forming maleimide functionalized polymers are provided. In one such embodiment, a maleimide functionalized polymer is prepared in a method that includes a step of carrying out a reverse Diels-Alder reaction. Intermediates useful in the methods, as well as methods for preparing the intermediates, are also provided. Also provided are polymeric reagents, methods of using polymeric reagents, compounds and conjugates.

  提供了制备马来酰亚胺官能化聚合物的方法。在其中一种实施例中，通过进行反Diels-Alder反应的步骤来准备马来酰亚胺官能化聚合物。还提供了在该方法中有用的中间体，以及制备中间体的方法。还提供了聚合物试剂、使用聚合物试剂的方法、化合物和共轭物。
• Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
  申请人：Köster Hubert

  公开号：US20110118136A1

  公开（公告）日：2011-05-19

  Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for analyzing complex protein mixtures, such as the proteome. The compounds are multifunctional reagents that provide for the separation and isolation of complex protein mixtures. Each compound has the formula: wherein: Z is a trityl derivative; X, the reactivity function, covalently binds to amino acid side chains of proteins; Y, the selectivity function, modulates binding of X to the amino acid side chains in proteins such that X binds to fewer proteins when Y is present than in its absence; and Q permits separation or immobilization of the capture compound. Automated systems for performing the methods also are provided.

  本文提供了捕获化合物和化合物集合以及使用这些化合物进行生物分子分析的方法。特别地，提供了用于分析复杂蛋白质混合物（如蛋白质组）的集合、化合物和方法。这些化合物是多功能试剂，可用于分离和分离复杂蛋白质混合物。每个化合物的公式为：其中：Z是三苯甲基衍生物；X是反应性功能，共价结合到蛋白质的氨基酸侧链上；Y是选择性功能，调节X与蛋白质中氨基酸侧链的结合，使得在Y存在时，X与较少的蛋白质结合，而在Y不存在时，X与更多的蛋白质结合；Q允许分离或固定捕获化合物。本文还提供了用于执行这些方法的自动化系统。
• RUBBER COMPOSITION AND PNEUMATIC TIRE
  申请人：Sumitomo Rubber Industries, Ltd.

  公开号：EP3006493B1

  公开（公告）日：2017-08-30
• Use of copolymers as auxiliary agents for producing leather
  申请人：Schneider Tanja

  公开号：US20070078226A1

  公开（公告）日：2007-04-05

  Graft copolymers which contain at least one monoethylenically unsaturated monomer comprising at least one nitrogen-containing heterocycle are used as assistants for leather production.